Malondialdehyde-Induced Post-Translational Modification of Human Hemoglobin.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.2c00764
Abstract: Lysine residues in proteins undergo multiple enzymatic and nonenzymatic post-translational modifications (PTMs). The terminal ε amine group of lysine residues in proteins is carbonylated chemically by carbonyl species such as glyoxal (GO; OCH–CHO, C2H2O2; MW… read more here.
Keywords: mda; malondialdehyde induced; post translational; plasma serum ... See more keywords
Selective Radical Trifluoromethylation of Native Residues in Proteins
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.7b10230
Abstract: The incorporation of fluorine can not only significantly facilitate the study of proteins but also potentially modulate their function. Though some biosynthetic methods allow global residue-replacement, post-translational fluorine incorporation would constitute a fast and efficient… read more here.
Keywords: selective radical; trifluoromethylation; residues proteins; radical trifluoromethylation ... See more keywords