Chemistry and biological activity of resin glycosides from Convolvulaceae species
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DOI: 10.1002/med.21916
Abstract: Carbohydrate‐based drug discovery has gained more and more attention during the last few decades. Resin glycoside is a kind of novel and complex glycolipids mainly distributed in plants of the family Convolvulaceae. Over the last… read more here.
Keywords: chemistry; biological activity; chemistry biological; resin ... See more keywords
Calysepins I-VII, Hexasaccharide Resin Glycosides from Calystegia sepium and Their Cytotoxic Evaluation.
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DOI: 10.1021/acs.jnatprod.2c00008
Abstract: Seven new hexasaccharide resin glycosides, named calysepins I-VII (1-7), with 27-membered rings, were obtained from the aerial parts of Calystegia sepium. Their structures with absolute configuration were established on the basis of spectroscopic data interpretation… read more here.
Keywords: hexasaccharide resin; calystegia sepium; resin glycosides; calysepins vii ... See more keywords
Resin Glycosides from Operculina hamiltonii and Their Synergism with Vinblastine in Cancer Cells.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of natural products"
DOI: 10.1021/acs.jnatprod.2c00594
Abstract: Operculina hamiltonii is a vine native to the north and northeast region of Brazil, where its roots are traded as a depurative and laxative remedy with the name of Brazilian jalap in traditional medicine. Procedures… read more here.
Keywords: hamiltonii synergism; synergism vinblastine; glycosides operculina; operculina hamiltonii ... See more keywords
Resin Glycosides from the Roots of Operculina macrocarpa (Brazilian Jalap) with Purgative Activity.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of natural products"
DOI: 10.1021/acs.jnatprod.9b00222
Abstract: Analysis of the methanol-soluble resin glycosides from the roots of Operculina macrocarpa was assessed by generating NMR profiles of five glycosidic acids obtained through saponification, acetylation, and recycling HPLC purification. Operculinic acid H (1), two… read more here.
Keywords: resin; operculina macrocarpa; glycosides roots; resin glycosides ... See more keywords
Pentasaccharide resin glycosides with multidrug resistance reversal activities from the seeds of Pharbitis nil
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DOI: 10.1039/c7ra09026a
Abstract: Resin glycosides are novel P-glycoprotein inhibitors. In order to evaluate their multidrug resistance (MDR) reversal activities, we isolated seven new resin glycosides, pharbitins A–G (1–7) from the seeds of Pharbitis nil. Their chemical structures were… read more here.
Keywords: multidrug resistance; mdr reversal; resin glycosides; reversal activities ... See more keywords
Three new resin glycosides compounds from Argyreia acuta and their α-glucosidase inhibitory activity
Sign Up to like & getrecommendations! Published in 2017 at "Natural Product Research"
DOI: 10.1080/14786419.2016.1201669
Abstract: Abstract Three new phenolic compounds, acutacoside C (1), acutacoside D (2) and acutacoside E (3) were isolated from the aerial part of Argyreia acuta. The oligosaccharide chain was composed of two glucoses and three rhamnoses,… read more here.
Keywords: three new; resin glycosides; argyreia acuta; inhibitory ... See more keywords
Two new resin glycosides, muricatins XII and XIII, from the seeds of Ipomoea muricata.
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DOI: 10.1080/14786419.2022.2125970
Abstract: Two new resin glycosides, muricatins XII (1) and XIII (2), were isolated from the crude resin glycoside fraction of the seeds of Ipomoea muricata (L.) Jacq. (Convolvulaceae), along with three known ones, muricatins V (3),… read more here.
Keywords: glycosides muricatins; muricatins xii; two new; resin ... See more keywords
In vitro lipase inhibition and in silico modelling analysis of the resin glycosides from the seeds of Ipomoea muricata and pharbitin from Pharbitidis Semen.
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DOI: 10.1080/14786419.2025.2495162
Abstract: Resin glycosides (RGs) are the unique constituents of Convolvulaceae plants. This study aims to investigate the inhibitory effects of the RG fraction from Ipomoea muricata seeds (IMRG) and that of pharbitin from Pharbitidis Semen (seeds… read more here.
Keywords: resin glycosides; inhibition; pharbitin pharbitidis; ipomoea muricata ... See more keywords
Progress in the total synthesis of resin glycosides
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Chemistry"
DOI: 10.3389/fchem.2022.1036954
Abstract: Resin glycosides, mainly distributed in plants of the family Convolvulaceae, are a class of novel and complex glycolipids. Their structural complexity and significant biological activities have received much attention from synthetic chemists, and a number… read more here.
Keywords: progress total; resin; resin glycosides; synthesis resin ... See more keywords
Resin Glycosides with α-Glucosidase and Protein Tyrosine Phosphatase 1B Inhibitory Activities from the Seeds of Cuscuta japonica
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DOI: 10.3390/biom15101465
Abstract: In the present study, seven previously undescribed resin glycosides, designated cusponins I-VII (1–7), together with one known analog (8), were isolated from the seeds of Cuscuta japonica, a traditional medicine used in China. Structural elucidation… read more here.
Keywords: resin glycosides; seeds cuscuta; cuscuta japonica; protein tyrosine ... See more keywords
Mass Defect Filtering-Oriented Identification of Resin Glycosides from Root of Convolvulus scammonia Based on Quadrupole-Orbitrap Mass Spectrometer
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DOI: 10.3390/molecules27113638
Abstract: This work aimed to develop and evaluate a post-acquisition data processing strategy, referred to as a mass defect filter (MDF), for rapid target the resin glycosides in root of Convolvulus scammonia by setting mass rang… read more here.
Keywords: glycosides root; root convolvulus; resin glycosides; mass ... See more keywords