High-Integrity Nanoformulation of Resiquimod (R848) for Dual Autophagy Activation and PD-L1 Modulation in Triple-Negative Breast Cancer.
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DOI: 10.1002/mabi.202500388
Abstract: Triple‐negative breast cancer (TNBC) remains a formidable clinical challenge due to its molecular heterogeneity and resistance to conventional therapies. This study presents a high‐integrity nanoemulsion (NE) formulation designed to enhance the delivery and stability of… read more here.
Keywords: breast cancer; high integrity; negative breast; resiquimod r848 ... See more keywords
Systemic Administration of the TLR7/8 Agonist Resiquimod (R848) to Mice Is Associated with Transient, In Vivo-Detectable Brain Swelling
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DOI: 10.3390/biology11020274
Abstract: Simple Summary Physiological changes to the body can affect the brain. For example, inflammation that originates in the body can be sensed by the brain. In this study, we used an agent called resiquimod (R848)… read more here.
Keywords: mice; brain swelling; administration; resiquimod r848 ... See more keywords