Abstract IA08: Engineering T cells to resist and convert immunosuppressive tumor microenvironments
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DOI: 10.1158/2326-6074.tumimm17-ia08
Abstract: A major challenge in adoptive T-cell therapy for solid tumors is the harsh immunosuppressive tumor microenvironment. Soluble factors such as transforming growth factor beta (TGF-β) play key roles in tumor immune evasion. Here, we report… read more here.
Keywords: resist convert; immunosuppressive tumor; cells resist; engineering cells ... See more keywords