Role of AcrAB-TolC multidrug efflux pump in drug-resistance acquisition by plasmid transfer
Sign Up to like & getrecommendations! Published in 2019 at "Science"
DOI: 10.1126/science.aav6390
Abstract: A race against time Clinically relevant antimicrobial resistance is largely spread via plasmids that disperse among bacteria during conjugation. How quickly can a resistance gene be expressed after transfer? In susceptible bacterial cells, tetracycline should… read more here.
Keywords: efflux pump; resistance acquisition; resistance; acrab tolc ... See more keywords
HopE and HopD Porin-Mediated Drug Influx Contributes to Intrinsic Antimicrobial Susceptibility and Inhibits Streptomycin Resistance Acquisition by Natural Transformation in Helicobacter pylori
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DOI: 10.1128/spectrum.01987-21
Abstract: Helicobacter pylori is constitutively competent for natural transformation (NT) and possesses an efficient system for homologous recombination, which could be utilized to study the NT-mediated horizontal gene transfer induced antibiotic resistance acquisition. Bacterial porins have… read more here.
Keywords: hope hopd; resistance; resistance acquisition;
Single-Cell FISH Analysis Reveals Distinct Shifts in PKM Isoform Populations during Drug Resistance Acquisition
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DOI: 10.3390/biom12081082
Abstract: The Warburg effect, i.e., the utilization of glycolysis under aerobic conditions, is recognized as a survival advantage of cancer cells. However, how the glycolytic activity is affected during drug resistance acquisition has not been explored… read more here.
Keywords: resistance acquisition; cell; single cell; drug resistance ... See more keywords