Cell permeability, β-lactamase activity, and transport contribute to high level of resistance to ampicillin in Lysobacter enzymogenes
Sign Up to like & getrecommendations! Published in 2019 at "Applied Microbiology and Biotechnology"
DOI: 10.1007/s00253-019-10266-7
Abstract: Discovery of multidrug resistance (MDR) in environmental microorganisms provides unique resources for uncovering antibiotic resistomes, which could be vital to predict future emergence of MDR pathogens. Our previous studies indicated that Lysobacter sp. conferred intrinsic… read more here.
Keywords: ampicillin; lysobacter enzymogenes; ampicillin lysobacter; resistance ampicillin ... See more keywords
Substitutions in PBP3 confer resistance to both ampicillin and extended‐spectrum cephalosporins in Haemophilus parainfluenzae as revealed by site‐directed mutagenesis and gene recombinants
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Antimicrobial Chemotherapy"
DOI: 10.1093/jac/dkx157
Abstract: Objectives: To determine the association of amino acid substitutions in PBP3 with &bgr;‐lactam susceptibility in Haemophilus parainfluenzae. Methods: Single and multiple amino acid mutations at positions 385, 511 and 526 were introduced into PBP3 of… read more here.
Keywords: directed mutagenesis; resistance ampicillin; resistance; substitutions pbp3 ... See more keywords