Nonlocal Effects of Antibiotic-Resistance-Causing Mutations Reveal an Alternative Region for Targeting on FtsW-Penicillin-Binding Protein 3 Complex of Haemophilus influenzae
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DOI: 10.1021/acs.jcim.3c00127
Abstract: Currently prescribed antibiotics target the catalytic sites of wild-type bacterial proteins; however, bacteria adopt mutations at this site, eventually leading to the emergence of resistance. Therefore, the identification of alternative drug binding sites is crucial,… read more here.
Keywords: binding protein; haemophilus influenzae; resistance causing; resistance ... See more keywords