DRES-03. PARP INHIBITOR, INHIBITION OF HOMOLOGOUS RECOMBINATION, OR DIANHYDRODULCITOL CAN OVERCOME TEMOZOLOMIDE-RESISTANCE IN GLIOMA CELLS
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DOI: 10.1093/neuonc/noz175.291
Abstract: Glioblastoma is one of the most aggressive tumors in the central nervous system tumors, with 5-year survival rates of less than 10%. The standard therapy for glioblastomas is maximal safe resection, followed by radiation therapy… read more here.
Keywords: inhibition; resistance glioma; parp inhibitor; glioma cells ... See more keywords
MiR-526b-3p Inhibits the Resistance of Glioma Cells to Adriamycin by Targeting MAPRE1
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DOI: 10.1155/2022/2402212
Abstract: Background Cell resistance is the main reason for the high mortality in glioma. Adriamycin (ADR) is a treatment drug for glioma and often leads to chemoresistance. Previous studies have confirmed that the abnormal expression of… read more here.
Keywords: mir 526b; cell; resistance glioma; glioma cells ... See more keywords
LINC00883 Promotes Drug Resistance of Glioma Through a microRNA-136/NEK1-Dependent Mechanism
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DOI: 10.3389/fonc.2021.692265
Abstract: Objective Accumulating evidence has highlighted the roles of long noncoding RNAs (lncRNAs) as competing endogenous RNAs (ceRNAs) of microRNAs (miRNAs) through their binding sites in the progression of glioma. Hereby, we aim to explore the… read more here.
Keywords: resistance glioma; mir 136; glioma; drug ... See more keywords
HOTTIP Mediated Therapy Resistance in Glioma Cells Involves Regulation of EMT-Related miR-10b
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DOI: 10.3389/fonc.2022.873561
Abstract: The advanced grade glioblastomas are characterized by dismal five-year survival rates and are associated with worse outcomes. Additionally, resistance to therapies is an additional burden responsible for glioma associated mortality. We studied the resistance against… read more here.
Keywords: mir 10b; resistance glioma; glioma cells; hottip ... See more keywords
CD147 confers temozolomide resistance of glioma cells via the regulation of β-TrCP/Nrf2 pathway
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DOI: 10.7150/ijbs.60894
Abstract: Background: Drug resistance is one of the biggest challenges in cancer therapy. temozolomide (TMZ) represents the most important chemotherapeutic option for glioma treatment. However, the therapeutic efficacy of TMZ remains very limited due to its… read more here.
Keywords: glioma; cd147; resistance glioma; tmz ... See more keywords