High efficacy of Resistance-guided retreatment of HCVpatients failing NS5A inhibitors in real world.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of hepatology"
DOI: 10.1016/j.jhep.2019.06.022
Abstract: BACKGROUND Most hepatitis C virus (HCV) infected patients failing NS5A inhibitors develop resistance-associated substitutions (RASs). Here we report the use of resistance-guided retreatment of patients who failed prior NS5A inhibitor-containing regimens in the GEHEP-004 cohort.… read more here.
Keywords: ribavirin; resistance guided; failing ns5a; report ... See more keywords
Self-resistance guided genome mining uncovers new topoisomerase inhibitors from myxobacteria† †Electronic supplementary information (ESI) available. CCDC 1831467 and 1831468. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c8sc01325j
Sign Up to like & getrecommendations! Published in 2018 at "Chemical Science"
DOI: 10.1039/c8sc01325j
Abstract: Mining the genome to harvest from the metabolome: a well-directed search for bioactive natural products unearths the pyxidicyclines from Pyxidicoccus. read more here.
Keywords: resistance guided; genome mining; uncovers new; mining uncovers ... See more keywords
LB1.4 Improved outcomes following resistance-guided treatment of mycoplasma genitalium infection
Sign Up to like & getrecommendations! Published in 2017 at "Sexually Transmitted Infections"
DOI: 10.1136/sextrans-2017-053264.105
Abstract: Introduction Resistance to 1 st (azithromycin) and 2nd line (moxifloxacin) therapy in Mycoplasma genitalium (MG) now exceeds 50% and 15%, respectively, in the Asia-Pacific region. New approaches to achieve high levels of cure and minimise resistance… read more here.
Keywords: resistance guided; mycoplasma genitalium; resistance; doxycycline ... See more keywords