Recombinase-mediated cassette exchange-based screening of a CRISPR/Cas9 library for enhanced recombinant protein production in human embryonic kidney cells: Improving resistance to hyperosmotic stress.
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DOI: 10.1016/j.ymben.2022.03.017
Abstract: Targeted engineering of mammalian cells has been widely attempted to ensure the efficient production of therapeutic proteins with proper quality during bioprocesses. However, the identification of novel targets for cell engineering is labor-intensive and has… read more here.
Keywords: hyperosmotic stress; resistance hyperosmotic; production; stress ... See more keywords