Resistance in Patients Failing Integrase Strand Transfer Inhibitors: A Call to Replace Raltegravir With Dolutegravir in Third-Line Treatment in South Africa
Sign Up to like & getrecommendations! Published in 2019 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofz377
Abstract: Abstract Data on integrase resistance patterns in low- and middle-income countries (LMICs) is scarce. We assessed genotypic drug resistance in 43 patients with virological failure on integrase strand transfer inhibitors (INSTIs) containing regimens as part… read more here.
Keywords: integrase; resistance patients; strand transfer; transfer inhibitors ... See more keywords
Cumulative inflammatory burden and obesity as determinants of insulin resistance in patients with established rheumatoid arthritis: cross-sectional study
Sign Up to like & getrecommendations! Published in 2021 at "BMJ Open"
DOI: 10.1136/bmjopen-2020-044749
Abstract: Objectives To describe the prevalence of insulin resistance (IR) in patients with established rheumatoid arthritis (RA) and to analyse the contribution of cumulative inflammatory burden and other factors to its development. Design Observational cross-sectional study.… read more here.
Keywords: resistance patients; patients established; rheumatoid arthritis; insulin resistance ... See more keywords
FSCN1 Promotes Radiation Resistance in Patients With PIK3CA Gene Alteration
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2021.653005
Abstract: Radiotherapy is one of the standard treatments for cervical cancer and head and neck cancer. However, the clinical efficacy of this treatment is limited by radioresistance. The discovery of effective prognostic biomarkers and the identification… read more here.
Keywords: radiation resistance; promotes radiation; patients pik3ca; fscn1 promotes ... See more keywords
Antibiotic Resistance in Patients with Cystic Fibrosis: Past, Present, and Future
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DOI: 10.3390/antibiotics12020217
Abstract: Patients with cystic fibrosis (CF) are repeatedly exposed to antibiotics, especially during the pulmonary exacerbations of the disease. However, the available therapeutic strategies are frequently inadequate to eradicate the involved pathogens and most importantly, facilitate… read more here.
Keywords: antibiotic resistance; patients cystic; resistance; resistance patients ... See more keywords
Predictors of Pharmaco-Resistance in Patients with Post-Stroke Epilepsy
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DOI: 10.3390/brainsci11040418
Abstract: Objectives: The study aimed to explore the clinical predictors of pharmaco-resistance in patients with post-stroke epilepsy (PSE). Methods: Patients with epilepsy secondary to cerebral infarct or spontaneous intracerebral hemorrhage were included. The study outcome was… read more here.
Keywords: post stroke; pharmaco resistance; resistance patients; patients post ... See more keywords
REVEALING THE MOLECULAR-GENETIC AND CLINICAL PREDICTORS OF GLUCOCORTICOID RESISTANCE IN PATIENTS WITH HAND ECZEMA.
Sign Up to like & getrecommendations! Published in 2022 at "Wiadomosci lekarskie"
DOI: 10.36740/wlek202209105
Abstract: OBJECTIVE The aim: To reveal the possible predictors of the glucocorticoid resistance in patients with hand eczema (HE) based on the demographic, clinical, and molecular-genetic data. PATIENTS AND METHODS Materials and methods: 143 patients with… read more here.
Keywords: glucocorticoid resistance; predictors glucocorticoid; resistance patients; resistance ... See more keywords