Abstract B14: Activation of the MACC1/PIM/cMyc axis confers resistance to PI3K/mTOR inhibition in PIK3CA mutant NSCLC
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DOI: 10.1158/1557-3125.pi3k-mtor18-b14
Abstract: Introduction: The PI3K pathway is often dysregulated in lung cancer, making it an ideal therapeutic target. Pan- and isoform-specific inhibitors of the PI3K pathway are currently being evaluated in clinical trials. However, all patients treated… read more here.
Keywords: pik3ca mutant; resistance pi3k; macc1 pim; pi3k mtor ... See more keywords