Articles with "resistance plx8394" as a keyword



Abstract 5523: Inhibition of FASN postpones development of resistance to PLX8394 in colorectal cancer

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Published in 2025 at "Cancer Research"

DOI: 10.1158/1538-7445.am2025-5523

Abstract: Mutations in proto-oncogene B-Raf (BRAF) occur in about 10% of colorectal cancer (CRC) patients and BRAFV600E is the most common type. This subset of CRC is associated with a reduced response to chemotherapy and poor… read more here.

Keywords: resistance; fasn; crc; resistance plx8394 ... See more keywords