NAD+ Cleavage: TIR Domain-Containing Resistance Proteins in Action.
Sign Up to like & getrecommendations! Published in 2019 at "Trends in plant science"
DOI: 10.1016/j.tplants.2019.10.005
Abstract: Plant resistance proteins play a key role in detecting pathogen infection and activating plant defense. Two recent papers by Horsefield et al. and Wan et al. revealed that the TIR domain in resistance (R) proteins functions as an NAD+-cleaving… read more here.
Keywords: tir domain; resistance proteins; resistance; nad cleavage ... See more keywords
Inhibition of multidrug resistance proteins by MK571 restored the erectile function in obese mice through cGMP accumulation
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DOI: 10.1111/andr.13340
Abstract: Intracellular levels of cyclic nucleotides can also be controlled by the action of multidrug resistance protein types 4 (MRP4) and 5 (MRP5). To date, no studies evaluated the role of their inhibition in an animal… read more here.
Keywords: multidrug resistance; resistance proteins; inhibition multidrug; multidrug ... See more keywords