Overcoming Stenotrophomonas maltophilia Resistance for a More Rational Therapeutic Approach
Sign Up to like & getrecommendations! Published in 2022 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofac095
Abstract: Abstract Stenotrophomonas maltophilia is an underappreciated source of morbidity and mortality among gram-negative pathogens. Effective treatment options with acceptable toxicity profiles are limited. Phenotypic susceptibility testing via commercial automated test systems is problematic and no… read more here.
Keywords: resistance rational; maltophilia resistance; overcoming stenotrophomonas; rational therapeutic ... See more keywords
Abstract SY32-03: Overcoming PARP inhibitor resistance through rational combinations in the clinic
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-sy32-03
Abstract: Genomic instability is a key hallmark of cancer that arises owing to defects in the DNA damage response (DDR) and/or increased replication stress. The therapeutic landscape of antitumor agents targeting the DDR has rapidly expanded… read more here.
Keywords: resistance rational; inhibitor resistance; parp inhibitor; overcoming parp ... See more keywords