Articles with "resistance related" as a keyword



Insulin Resistance-Related Cardiometabolic Risk Among Nondiabetic Childbearing Age Females

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Published in 2024 at "Metabolic Syndrome and Related Disorders"

DOI: 10.1089/met.2024.0009

Abstract: Background: This study evaluates insulin resistance prevalence in young females without diabetes, assessing risk factors and adiposity indices for early detection of cardiometabolic disorders. Methods: A cross-sectional study was conducted, involving 282 females aged 18–35… read more here.

Keywords: young females; insulin resistance; risk; resistance related ... See more keywords

Establishment of a five‐enzalutamide‐resistance‐related‐gene‐based classifier for recurrence‐free survival predicting of prostate cancer

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Published in 2022 at "Journal of Cellular and Molecular Medicine"

DOI: 10.1111/jcmm.17554

Abstract: To identify prostate cancer (PCa) patients with a high risk of recurrence is critical before delivering adjuvant treatment. We developed a classifier based on the Enzalutamide treatment resistance‐related genes to assist the currently available staging… read more here.

Keywords: resistance related; recurrence; based classifier; prostate cancer ... See more keywords

Identification and validation of a lenvatinib resistance-related prognostic signature in HCC, in which PFKFB4 contributes to tumor progression and lenvatinib resistance

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Published in 2025 at "BMC Gastroenterology"

DOI: 10.1186/s12876-025-03861-8

Abstract: Drug resistance reflects the evolution of tumors and represents the leading factor behind recurrence and death. Lenvatinib is the first-line therapy for hepatocellular carcinoma (HCC), but its effectiveness is limited by rapid development of resistance.… read more here.

Keywords: resistance; lenvatinib resistance; hcc; resistance related ... See more keywords
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Underlying mechanism of sorafenib resistance in hepatocellular carcinoma: a bioinformatics study based on validated resistance-related genes.

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Published in 2021 at "Journal of gastrointestinal oncology"

DOI: 10.21037/jgo-21-377

Abstract: Background Sorafenib, the first approved targeted therapy for advanced hepatocellular carcinoma (HCC), is often reported to comprised survival-benefit due to resistance. An underlying mechanism of resistance was proposed using bioinformatics analysis based on differentially expressed… read more here.

Keywords: hepatocellular carcinoma; mechanism; resistance related; resistance ... See more keywords

Identification of Gefitinib Resistance-Related lncRNA-miRNA-mRNA Regulatory Networks and Corresponding Prognostic Signature in Patients with Lung Adenocarcinoma

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Published in 2022 at "International Journal of General Medicine"

DOI: 10.2147/ijgm.s369718

Abstract: Purpose To identify and characterize gefitinib resistance-related (GefR-related) lncRNAs and construct a prediction model for lung adenocarcinoma (LUAD). Methods Differential expression analysis between PC9 and gefitinib-resistant PC9 (PC9GR) cell samples was performed to screen GefR-related… read more here.

Keywords: resistance related; signature; prognostic signature; gefr related ... See more keywords

Preliminary analysis of the response of tobacco hormonal pathway salicylic acid and jasmonic acid resistance-related genes to Exserohilum turcicum

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Published in 2024 at "Pakistan Journal of Botany"

DOI: 10.30848/pjb2025-2(22)

Abstract: Non-host disease resistance (NHR) is a broad-spectrum disease resistance in plants stimulated by non-adapted pathogenic with persistent disease resistance properties. In recent years, NHR has been considered as a new strategy for disease control. In… read more here.

Keywords: disease; resistance; resistance related; tobacco ... See more keywords

Delamanid, Bedaquiline, and Linezolid Minimum Inhibitory Concentration Distributions and Resistance-related Gene Mutations in Multidrug-resistant and Extensively Drug-resistant Tuberculosis in Korea

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Published in 2018 at "Annals of Laboratory Medicine"

DOI: 10.3343/alm.2018.38.6.563

Abstract: Background Delamanid, bedaquiline, and linezolid have recently been approved for the treatment of multidrug- and extensively drug-resistant (MDR and XDR, respectively) tuberculosis (TB). To use these drugs effectively, drug susceptibility tests, including rapid molecular techniques,… read more here.

Keywords: delamanid bedaquiline; resistance related; bedaquiline linezolid; drug ... See more keywords

Identifying the HIV-Resistance-Related Factors and Regulatory Network via Multi-Omics Analyses

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Published in 2024 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms252111757

Abstract: For research on HIV/AIDS, it is important to elucidate the complex viral–host interaction, host dependency factors (HDFs), and restriction factors. However, the regulatory network of HIV-resistance-related factors remains not well understood. Therefore, we integrated four… read more here.

Keywords: resistance; related factors; resistance related; hiv resistance ... See more keywords

Construction and Validation of an Oxaliplatin-Resistant Gene Signature in Colorectal Cancer Patients Who Underwent Chemotherapy

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Published in 2022 at "Pharmaceuticals"

DOI: 10.3390/ph15091139

Abstract: Aberrant expression of genes contributes to the chemoresistance of colorectal cancer (CRC) treatment. This study aimed to identify genes associated with the chemoresistance of oxaliplatin-based chemotherapy in CRC patients and to construct a signature. Oxaliplatin… read more here.

Keywords: resistance related; signature; oxaliplatin resistance; gene signature ... See more keywords