AZD9291 Resistance Reversal Activity of a pH‐Sensitive Nanocarrier Dual‐Loaded with Chloroquine and FGFR1 Inhibitor in NSCLC
Sign Up to like & getrecommendations! Published in 2021 at "Advanced Science"
DOI: 10.1002/advs.202002922
Abstract: Abstract AZD9291 can effectively prolong survival of non‐small cell lung cancer (NSCLC) patients. Unfortunately, the mechanism of its acquired drug resistance is largely unknown. This study shows that autophagy and fibroblast growth factor receptor 1… read more here.
Keywords: azd9291; resistance reversal; crgd; resistance ... See more keywords
Natural alkaloids as P-gp inhibitors for multidrug resistance reversal in cancer.
Sign Up to like & getrecommendations! Published in 2017 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2017.06.047
Abstract: The biggest challenge associated with cancer chemotherapy is the development of cross multi-drug resistance to almost all anti-cancer agents upon chronic treatment. The major contributing factor for this resistance is efflux of the drugs by… read more here.
Keywords: reversal cancer; natural alkaloids; resistance reversal; resistance ... See more keywords
Rare dimeric guaianes from Xylopia vielana and their multidrug resistance reversal activity.
Sign Up to like & getrecommendations! Published in 2019 at "Phytochemistry"
DOI: 10.1016/j.phytochem.2018.11.004
Abstract: Thirteen undescribed dimeric guaianes were isolated from the leaves of Xylopia vielana Pierre. Their structures were elucidated by NMR spectroscopy and mass spectrometry, and the absolute configurations of vielanins G-Q were determined by a combination… read more here.
Keywords: xylopia vielana; resistance reversal; spectroscopy; multidrug resistance ... See more keywords
Pt nanozyme for O2 self-sufficient, tumor-specific oxidative damage and drug resistance reversal
Sign Up to like & getrecommendations! Published in 2019 at "Nanoscale Horizons"
DOI: 10.1039/c9nh00088g
Abstract: A catalase and oxidase-mimetic Pt nanozyme was developed and demonstrated good drug resistance reversal ability. read more here.
Keywords: drug resistance; resistance reversal; nanozyme self;