Antimicrobial resistance and treatment: an unmet clinical safety need
Sign Up to like & getrecommendations! Published in 2018 at "Expert Opinion on Drug Safety"
DOI: 10.1080/14740338.2018.1488962
Abstract: ABSTRACT Introduction: Infections due to multidrug-resistant (MDR) bacteria are burdened by high mortality rates. The development of new compounds to face the global threat of resistance is urgently needed. Combination regimens including “old” high-dose antimicrobials… read more here.
Keywords: mdr; treatment unmet; safety; antimicrobial resistance ... See more keywords
Disseminating antibiotic resistance during treatment
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DOI: 10.1126/science.aax6620
Abstract: A multidrug efflux pump can help bacteria acquire antibiotic resistance through plasmid transfer The spread of antibiotic resistance in bacterial pathogens has become a major public health problem. Resistance genes to clinically relevant antibiotics are… read more here.
Keywords: disseminating antibiotic; resistance; antibiotic resistance; resistance treatment ... See more keywords
EMT-Inducing Transcription Factors, Drivers of Melanoma Phenotype Switching, and Resistance to Treatment
Sign Up to like & getrecommendations! Published in 2020 at "Cancers"
DOI: 10.3390/cancers12082154
Abstract: Transcription factors, extensively described for their role in epithelial–mesenchymal transition (EMT-TFs) in epithelial cells, also display essential functions in the melanocyte lineage. Recent evidence has shown specific expression patterns and functions of these EMT-TFs in… read more here.
Keywords: transcription factors; phenotype switching; resistance treatment;
[Prevalence of antiretroviral drug resistance in treatment-naive injecting drug users infected with HIV-1 in Guangzhou, 2008-2015].
Sign Up to like & getrecommendations! Published in 2019 at "Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi"
DOI: 10.3760/cma.j.issn.0254-6450.2019.02.014
Abstract: Objective: To understand the prevalence of drug resistance in treatment-naive injecting drug users (IDUs) infected with HIV-1 in Guangzhou. Methods: HIV-1 RNA were extracted from the serum specimens of the newly confirmed HIV-1 positive IDUs… read more here.
Keywords: drug resistance; prevalence; drug; guangzhou ... See more keywords