Compensation between CSF1R+ macrophages and Foxp3+ Treg cells drives resistance to tumor immunotherapy.
Sign Up to like & getrecommendations! Published in 2018 at "JCI insight"
DOI: 10.1172/jci.insight.120631
Abstract: Redundancy and compensation provide robustness to biological systems but may contribute to therapy resistance. Both tumor-associated macrophages (TAMs) and Foxp3+ regulatory T (Treg) cells promote tumor progression by limiting antitumor immunity. Here we show that… read more here.
Keywords: resistance tumor; treg cells; csf1r; foxp3 treg ... See more keywords
Emerging Bismuth Chalcogenides Based Nanodrugs for Cancer Radiotherapy
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.844037
Abstract: Radiotherapy (RT), as one of the main methods of clinical tumor treatment, has been applied to the treatment of most solid tumors. However, the effect of RT is compromised by the radiation resistance of tumor… read more here.
Keywords: radiotherapy; based nanodrugs; resistance tumor; bismuth chalcogenides ... See more keywords