Association of Insulin Resistance and Type 2 Diabetes With Gut Microbial Diversity
Sign Up to like & getrecommendations! Published in 2021 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2021.18811
Abstract: Key Points Question Which gut microbial taxa are associated with the development of type 2 diabetes? Findings In this cross-sectional study of 2166 participants in 2 large population-based studies, lower microbiome Shannon index and richness… read more here.
Keywords: gut microbial; type diabetes; resistance type; insulin resistance ... See more keywords
Alström syndrome: an ultra-rare monogenic disorder as a model for insulin resistance, type 2 diabetes mellitus and obesity
Sign Up to like & getrecommendations! Published in 2021 at "Endocrine"
DOI: 10.1007/s12020-021-02643-y
Abstract: Alström syndrome (ALMS) is a monogenic ultra-rare disorder with a prevalence of one per million inhabitants caused by pathogenic variants of ALMS1 gene. ALMS1 is located on chromosome 2p13, spans 23 exons and encodes a… read more here.
Keywords: insulin; ultra rare; alstr syndrome; type diabetes ... See more keywords
Effects of carbon substitution for nitrogen on the pitting corrosion resistance of type UNS S32205 duplex stainless steel
Sign Up to like & getrecommendations! Published in 2020 at "Corrosion Science"
DOI: 10.1016/j.corsci.2019.108308
Abstract: Abstract The effects of C-substitution for N on the pitting corrosion resistance of type UNS S32205 duplex stainless steel (DSS) were investigated. It was found that the C-substituted DSS possessed higher resistance to pitting corrosion… read more here.
Keywords: pitting corrosion; corrosion; resistance type; corrosion resistance ... See more keywords
Intramyocellular lipid content and lipogenic gene expression responses following a single bout of resistance type exercise differ between young and older men
Sign Up to like & getrecommendations! Published in 2017 at "Experimental Gerontology"
DOI: 10.1016/j.exger.2017.03.018
Abstract: ABSTRACT The aim of this study was to examine the temporal relationship between intramyocellular lipid (IMCL) content and the expression of genes associated with IMCL turnover, fat metabolism, and inflammation during recovery from an acute… read more here.
Keywords: bout resistance; expression; resistance; resistance type ... See more keywords
Esculetin ameliorates insulin resistance and type 2 diabetic nephropathy through reversal of histone H3 acetylation and H2A lysine 119 monoubiquitination
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Functional Foods"
DOI: 10.1016/j.jff.2017.05.051
Abstract: Abstract Insulin resistance (IR) and type 2 diabetic nephropathy (T2DN) are associated with elevated renal expression of monocyte chemo-attractant protein (MCP1) and transforming growth factor-β (TGF-β). Posttranslational histone modifications (PTHMs) play significant role in regulating… read more here.
Keywords: type diabetic; resistance type; diabetic nephropathy; insulin resistance ... See more keywords
All about skin manifestations of insulin resistance and type 2 diabetes: acanthosis nigricans and acrochordons
Sign Up to like & getrecommendations! Published in 2019 at "Postgraduate Medical Journal"
DOI: 10.1136/postgradmedj-2019-136834
Abstract: A 47-year-old Romanian man was addressed to our department for severe hyperglycemia (22.5 mmol/L; HbA1c at 10.1%), leading to the diagnosis of type 2 diabetes in a context of android obesity with a body mass index… read more here.
Keywords: manifestations insulin; skin manifestations; type diabetes; resistance type ... See more keywords
Daily resistance-type exercise stimulates muscle protein synthesis in vivo in young men.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of applied physiology"
DOI: 10.1152/japplphysiol.00610.2017
Abstract: Resistance-type exercise increases muscle protein synthesis rates during acute postexercise recovery. The impact of resistance-type exercise training on (local) muscle protein synthesis rates under free-living conditions on a day-to-day basis remains unclear. We determined the… read more here.
Keywords: type exercise; exercise; resistance type; protein synthesis ... See more keywords
Distinctive Metabolomics Patterns Associated With Insulin Resistance and Type 2 Diabetes Mellitus
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2020.609806
Abstract: Obesity is associated with an increased risk of insulin resistance (IR) and type 2 diabetes mellitus (T2DM) which is a multi-factorial disease associated with a dysregulated metabolism and can be prevented in pre-diabetic individuals with… read more here.
Keywords: metabolites regulated; type diabetes; diabetes mellitus; resistance type ... See more keywords
Roles of Mitochondrial Sirtuins in Mitochondrial Function, Redox Homeostasis, Insulin Resistance and Type 2 Diabetes
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms21155266
Abstract: Mitochondria are the metabolic hubs that process a number of reactions including tricarboxylic acid cycle, β-oxidation of fatty acids and part of the urea cycle and pyrimidine nucleotide biosynthesis. Mitochondrial dysfunction impairs redox homeostasis and… read more here.
Keywords: insulin; mitochondrial sirtuins; type diabetes; resistance type ... See more keywords
The Role of Hypothalamic Microglia in the Onset of Insulin Resistance and Type 2 Diabetes: A Neuro-Immune Perspective
Sign Up to like & getrecommendations! Published in 2024 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms252313169
Abstract: Historically, microglial activation has been associated with diseases of a neurodegenerative and neuroinflammatory nature. Some, like Alzheimer’s disease, Parkinson’s disease, and multiple system atrophy, have been explored extensively, while others pertaining to metabolism not so… read more here.
Keywords: resistance; role; insulin resistance; resistance type ... See more keywords