Use of antibiotic disks to evolve drug-resistant bacteria
Sign Up to like & getrecommendations! Published in 2018 at "Antonie van Leeuwenhoek"
DOI: 10.1007/s10482-018-1055-3
Abstract: The methods used to generate antibiotic-resistant bacterial strains can be labour-intensive, costly, lengthy and/or prone to plate-to-plate variation. We propose a simple, inexpensive and easily replicated method to expose bacteria to a continuous gradient of… read more here.
Keywords: disks evolve; drug resistant; evolve drug; resistant ... See more keywords
Pathogenic multiple antimicrobial resistant Escherichia coli serotypes in recreational waters of Mumbai, India: a potential public health risk
Sign Up to like & getrecommendations! Published in 2017 at "Environmental Science and Pollution Research"
DOI: 10.1007/s11356-017-8760-8
Abstract: Globally, coastal waters have emerged into a pool of antibiotic resistance genes and multiple antibiotic resistant microorganisms, and pathogenicity of these resistant microorganisms in terms of serotypes and virulence genes has made the environment vulnerable.… read more here.
Keywords: risk; escherichia coli; coli; resistance ... See more keywords
Clinical isolates of Escherichia coli are resistant both to antibiotics and organotin compounds
Sign Up to like & getrecommendations! Published in 2019 at "Folia Microbiologica"
DOI: 10.1007/s12223-019-00707-1
Abstract: Antibiotic-resistant Escherichia coli are common causative agents of human urinary tract infections. Organotin compounds (OTCs) are man-made chemicals that may affect the renal function of exposed humans and rodents. OTCs are widely recognized as bactericides.… read more here.
Keywords: escherichia coli; intermediate resistant; organotin compounds; clinical isolates ... See more keywords
Epidemiology of antibiotic-resistant wound infections from six countries in Africa
Sign Up to like & getrecommendations! Published in 2018 at "BMJ Global Health"
DOI: 10.1136/bmjgh-2017-000475
Abstract: Introduction Little is known about the antimicrobial susceptibility of common bacteria responsible for wound infections from many countries in sub-Saharan Africa. Methods We performed a retrospective review of microbial isolates collected based on clinical suspicion… read more here.
Keywords: wound infections; country; epidemiology; resistant ... See more keywords
A scalable metabolite supplementation strategy against antibiotic resistant pathogen Chromobacterium violaceum induced by NAD+/NADH+ imbalance
Sign Up to like & getrecommendations! Published in 2017 at "BMC Systems Biology"
DOI: 10.1186/s12918-017-0427-z
Abstract: BackgroundThe leading edge of the global problem of antibiotic resistance necessitates novel therapeutic strategies. This study develops a novel systems biology driven approach for killing antibiotic resistant pathogens using benign metabolites.ResultsControlled laboratory evolutions established chloramphenicol… read more here.
Keywords: nad nadh; antibiotic resistant; biology; resistance ... See more keywords
Evaluating the Role of Wastewaters as Reservoirs of Antibiotic-Resistant ESKAPEE Bacteria Using Phenotypic and Molecular Methods
Sign Up to like & getrecommendations! Published in 2022 at "Infection and Drug Resistance"
DOI: 10.2147/idr.s368886
Abstract: Introduction Wastewaters carrying thousands of human specimens from the community and representing the diversity of antibiotic-resistant bacteria (ARB) and antibiotic-resistance genes (ARGs) directly from the community mirror the extent of AR spread in the community… read more here.
Keywords: eskapee bacteria; resistant eskapee; resistant; resistance ... See more keywords
Epidemiological and Antimicrobial Resistant Patterns, and Molecular Mechanisms of Carbapenem-Resistant Klebsiella pneumoniae Infections in ICU Patients
Sign Up to like & getrecommendations! Published in 2023 at "Infection and Drug Resistance"
DOI: 10.2147/idr.s410657
Abstract: Objective To study the epidemiological and antimicrobial resistant patterns, clinical characteristics and risk factors of critically ill patients infected with carbapenem-resistant Klebsiella pneumoniae (CRKP) from intensive care units (ICUs). The potential molecular mechanisms of antimicrobial… read more here.
Keywords: pneumoniae; epidemiological antimicrobial; resistant; resistance ... See more keywords
Prophylaxis and Treatment against Klebsiella pneumoniae: Current Insights on This Emerging Anti-Microbial Resistant Global Threat
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22084042
Abstract: Klebsiella pneumoniae (Kp) is an opportunistic pathogen and the leading cause of healthcare-associated infections, mostly affecting subjects with compromised immune systems or suffering from concurrent bacterial infections. However, the dramatic increase in hypervirulent strains and… read more here.
Keywords: resistant; klebsiella pneumoniae; anti microbial; threat ... See more keywords
Targeting Glutaminolysis Shows Efficacy in Both Prednisolone-Sensitive and in Metabolically Rewired Prednisolone-Resistant B-Cell Childhood Acute Lymphoblastic Leukaemia Cells
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24043378
Abstract: The prognosis for patients with relapsed childhood acute lymphoblastic leukaemia (cALL) remains poor. The main reason for treatment failure is drug resistance, most commonly to glucocorticoids (GCs). The molecular differences between prednisolone-sensitive and -resistant lymphoblasts… read more here.
Keywords: cell; prednisolone; childhood acute; lymphoblastic leukaemia ... See more keywords