Isolation and genomic analysis of temperate phage 5W targeting multidrug-resistant Acinetobacter baumannii.
Sign Up to like & getrecommendations! Published in 2021 at "Archives of microbiology"
DOI: 10.1007/s00203-021-02618-7
Abstract: Temperate phages are potential therapeutic agents, but only a few temperate phages infecting multidrug-resistant Acinetobacter baumannii have been identified. In this study, we isolated 5W, a temperate phage that infects multidrug-resistant A. baumannii, from pond… read more here.
Keywords: temperate phage; acinetobacter baumannii; baumannii; multidrug resistant ... See more keywords
Can Drug Repurposing be Effective Against Carbapenem-Resistant Acinetobacter baumannii?
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DOI: 10.1007/s00284-021-02693-5
Abstract: Carbapenem-resistant Acinetobacter baumannii has been classified as a top priority for the development of new therapies due to its resistance to most antibiotics. Drug repurposing may be a fast and inexpensive strategy for treating this… read more here.
Keywords: carbapenem resistant; carbapenem; acinetobacter baumannii; drug repurposing ... See more keywords
Polyclonal predominance of concurrently producing OXA-23 and OXA-58 carbapenem-resistant Acinetobacter baumannii strains in a pediatric intensive care unit
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Biology Reports"
DOI: 10.1007/s11033-019-04744-4
Abstract: We report a predominance (64.7%) of polyclonal carbapenem-resistant Acinetobacter baumannii (CRAB) strains concurrently producing OXA-23 and OXA-58 carbapenemases in a pediatric intensive care unit in an endemic area. This is the first report of emergence… read more here.
Keywords: resistant acinetobacter; concurrently producing; unit; producing oxa ... See more keywords
Combating tigecycline resistant Acinetobacter baumannii: A leap forward towards multi‐epitope based vaccine discovery
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Pharmaceutical Sciences"
DOI: 10.1016/j.ejps.2019.02.023
Abstract: ABSTRACT Global emergence of Tigecycline resistant Acinetobacter baumannii (TRAB) is on the horizon and poses a very serious threat to human health. There is a pressing demand for suitable therapeutics against this pathogen, particularly a… read more here.
Keywords: resistant acinetobacter; tigecycline resistant; vaccine; acinetobacter baumannii ... See more keywords
Pharmacodynamics of tigecycline alone and in combination with colistin against clinical isolates of multidrug-resistant Acinetobacter baumannii in an in vitro pharmacodynamic model.
Sign Up to like & getrecommendations! Published in 2017 at "International journal of antimicrobial agents"
DOI: 10.1016/j.ijantimicag.2017.01.007
Abstract: The objectives of this study, which were based on the hypothesis of mutant prevention concentration (MPC), were to compare tigecycline and colistin monotherapy and combination therapy against multidrug-resistant Acinetobacter baumannii (MDR-AB) and to identify changes… read more here.
Keywords: resistant acinetobacter; combination; colistin; multidrug resistant ... See more keywords
Activity of TP-6076 against carbapenem-resistant Acinetobacter baumannii isolates collected from inpatients in Greek hospitals.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of antimicrobial agents"
DOI: 10.1016/j.ijantimicag.2018.03.009
Abstract: TP-6076 is a synthetic fluorocycline antibiotic that inhibits bacterial protein synthesis. In this study, carbapenem-resistant Acinetobacter baumannii clinical isolates from 13 Greek hospitals were tested for susceptibility to TP-6076 and comparator antibiotics. Broth microdilution plates… read more here.
Keywords: resistant acinetobacter; carbapenem resistant; acinetobacter baumannii; mic90 ... See more keywords
Phenotypic and Molecular Characterisations of Carbapenem-resistant Acinetobacter baumannii Isolates Collected within the EURECA Study.
Sign Up to like & getrecommendations! Published in 2021 at "International journal of antimicrobial agents"
DOI: 10.1016/j.ijantimicag.2021.106345
Abstract: Multidrug-resistant Acinetobacter baumannii isolates are key pathogens that contribute to the global burden of antimicrobial resistance. This study aimed to investigate the phenotypic and molecular characteristics of carbapenem-resistant A. baumannii (CRAB) isolates from the EURECA… read more here.
Keywords: resistant acinetobacter; baumannii isolates; phenotypic molecular; acinetobacter baumannii ... See more keywords
Molecular epidemiology and genetic characterisation of carbapenem-resistant Acinetobacter baumannii isolates from Guangdong Province, South China.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of global antimicrobial resistance"
DOI: 10.1016/j.jgar.2018.11.002
Abstract: OBJECTIVES Carbapenem-resistant Acinetobacter baumannii (CRAB) has become a worldwide issue. This study aimed to characterise the epidemiology and genetic relationships of A. baumannii isolates in Guangdong Province, China. METHODS CRAB isolates were collected from five… read more here.
Keywords: resistant acinetobacter; guangdong province; epidemiology; carbapenem resistant ... See more keywords
Carbapenem-resistant Acinetobacter baumannii load in patients and their environment: the importance of detecting carriers.
Sign Up to like & getrecommendations! Published in 2023 at "Infection control and hospital epidemiology"
DOI: 10.1017/ice.2023.39
Abstract: The environment surrounding 30 of 31 carriers of carbapenem-resistant Acinetobacter baumannii (CRAB) was contaminated by CRAB. The environmental CRAB loads were similar whether carriers were identified only by surveillance cultures (nonclinical carriers) or also had… read more here.
Keywords: environment; acinetobacter baumannii; carbapenem resistant; resistant acinetobacter ... See more keywords
AdeIJK Pump-Specific Inhibitors Effective against Multidrug Resistant Acinetobacter baumannii.
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DOI: 10.1021/acsinfecdis.4c00190
Abstract: Multidrug-resistant Acinetobacter baumannii is a serious threat pathogen rapidly spreading in clinics and causing a range of complicated human infections. The major contributor to A. baumannii antibiotic resistance is the overproduction of AdeIJK and AdeABC… read more here.
Keywords: pump; acinetobacter baumannii; baumannii; resistant acinetobacter ... See more keywords
Exploiting human immune repertoire transgenic mice for protective monoclonal antibodies against antimicrobial resistant Acinetobacter baumannii
Sign Up to like & getrecommendations! Published in 2024 at "Nature Communications"
DOI: 10.1038/s41467-024-52357-8
Abstract: The use of monoclonal antibodies for the control of drug resistant nosocomial bacteria may alleviate a reliance on broad spectrum antimicrobials for treatment of infection. We identify monoclonal antibodies that may prevent infection caused by… read more here.
Keywords: mice; immune repertoire; acinetobacter baumannii; baumannii ... See more keywords