Commentary: Ketamine for Treatment-Resistant bipolar depression - need for more data!
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DOI: 10.1111/bdi.13129
Abstract: Treatment-resistant bipolar depression (TRBD) is a significant but less well-defined and quantified condition compared to treatment-resistant depression (TRD, unipolarity implied). Ketamine, a novel glutamatergic anesthetic agent repurposed as a rapid-acting antidepressant, is considered a third-line… read more here.
Keywords: depression; treatment resistant; bipolar depression; treatment ... See more keywords
Atypical idiopathic NBIA (neurodegeneration with brain iron accumulation) associated with treatment‐resistant bipolar mania responding to clozapine
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DOI: 10.1111/bdi.13262
Abstract: BACKGROUND Management of treatment-resistant bipolar mania has not been discussed much in the literature. The underlying degenerative neurological disorders could be one of the reasons for treatment resistance. METHODS A 27-year-old single male presented with… read more here.
Keywords: treatment; bipolar mania; resistant bipolar; treatment resistant ... See more keywords
Ketamine for Treatment‐Resistant bipolar depression—A reality check!
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DOI: 10.1111/bdi.13324
Abstract: Ketamine is a novel drug used for treatment- resistant depression. The initial randomized controlled trials (RCTs) established intravenous (IV) ketamine's rapid antidepressant effects for refrac-tory major depression, leading to its widespread use. However, the data… read more here.
Keywords: bipolar depression; ketamine; depression; treatment resistant ... See more keywords
Intravenous Ketamine Infusions in Treatment-Resistant Bipolar Depression: An Open-Label Naturalistic Observational Study
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DOI: 10.2147/ndt.s325000
Abstract: Purpose Bipolar disorder is a chronic and recurrent condition often associated with treatment resistance and suicidality. There is an unmet need for effective treatment in this group of patients. Ketamine has been demonstrated to have… read more here.
Keywords: treatment; resistant bipolar; treatment resistant; bipolar depression ... See more keywords
Safety and Tolerability of Ketamine Use in Treatment-Resistant Bipolar Depression Patients with Regard to Central Nervous System Symptomatology: Literature Review and Analysis
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DOI: 10.3390/medicina56020067
Abstract: The current psychopharmacological treatment approaches for major depression focus on monoaminergic interventions, which are ineffective in a large proportion of patients. Globally, treatment-resistant bipolar depression (TRBD) affects up to 33% of depressive patients receiving treatment.… read more here.
Keywords: symptomatology; depression; treatment resistant; treatment ... See more keywords