Emergence and Genomic Characterization of Neisseria gonorrhoeae Isolates with High Levels of Ceftriaxone and Azithromycin Resistance in Guangdong, China, from 2016 to 2019
Sign Up to like & getrecommendations! Published in 2022 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.01570-22
Abstract: Here, we report five sporadic dual-resistant isolates, including FC428-related ceftriaxone-resistant clones with MICs of ≥0.5 mg/L and high-level azithromycin resistance with MICs of ≥1,024 mg/L. This study highlights that dual-resistant clones with the same evolutionary origin as… read more here.
Keywords: guangdong china; resistant clones; fc428 related; resistance ... See more keywords
Drug resistance dependent on allostery: A P-loop rigor Eg5 mutant exhibits resistance to allosteric inhibition by STLC
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DOI: 10.3389/fonc.2022.965455
Abstract: The mitotic kinesin Eg5 has emerged as a potential anti-mitotic target for the purposes of cancer chemotherapy. Whether clinical resistance to these inhibitors can arise is unclear. We exploited HCT116 cancer cell line to select… read more here.
Keywords: loop; resistant clones; resistance; stlc ... See more keywords
Monitoring Colletotrichum Colonization and Reproduction in Different Rubber Tree Clones
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DOI: 10.3390/plants11070905
Abstract: Anthracnose, caused by fungi of the genus Colletotrichum, is present in the major rubber tree crop areas in Brazil, especially in São Paulo, Mato Grosso do Sul, Paraná, Minas Gerais, Espírito Santo, and northern states.… read more here.
Keywords: colonization reproduction; resistant clones; rubber; rubber tree ... See more keywords