MicroRNA-153-3p enhances the sensitivity of chronic myeloid leukemia cells to imatinib by inhibiting B-cell lymphoma-2-mediated autophagy
Sign Up to like & getrecommendations! Published in 2020 at "Human Cell"
DOI: 10.1007/s13577-020-00367-1
Abstract: Chronic myeloid leukemia (CML) is a hematopoietic stem cell disease caused by abnormal DNA replication of bone marrow stem cells and chemotherapy resistance is a major obstacle to the effective treatment of patients with CML.… read more here.
Keywords: resistant cml; cml; cml cells; mir 153 ... See more keywords
Isoalantolactone mediates the degradation of BCR-ABL protein in imatinib-resistant CML cells by down-regulating survivin.
Sign Up to like & getrecommendations! Published in 2023 at "Cell cycle"
DOI: 10.1080/15384101.2023.2209963
Abstract: Isoalantolactone (Iso) is a bioactive lactone isolated from the root of Inula helenium L, which has been reported to have many pharmacological effects. To investigate the role and mechanism of isoalantolactone in chronic myeloid leukemia… read more here.
Keywords: survivin; resistant cml; isoalantolactone; bcr abl ... See more keywords