Risk Factors for Isolation of Carbapenem-resistant Enterobacterales from Normally Sterile Sites and Urine.
Sign Up to like & getrecommendations! Published in 2021 at "American journal of infection control"
DOI: 10.1016/j.ajic.2021.12.007
Abstract: BACKGROUND Invasive infections caused by carbapenem-resistant Enterobacterales (CRE) are of significant concern in healthcare settings. We assessed risk factors for CRE culture from a sterile site (invasive infection) compared to isolation from urine in a… read more here.
Keywords: infection; risk factors; resistant enterobacterales; carbapenem resistant ... See more keywords
Occurrence and distribution of Carbapenem-resistant Enterobacterales and carbapenemase genes along a highly polluted hydrographic basin.
Sign Up to like & getrecommendations! Published in 2022 at "Environmental pollution"
DOI: 10.1016/j.envpol.2022.118958
Abstract: We determined the distribution and temporal variation of Carbapenem Resistant Enterobacterales (CRE), carbapenemase-encoding genes and other antibiotic resistance genes (ARGs) in a highly polluted river (Lis River; Portugal), also assessing the potential influence of water… read more here.
Keywords: carbapenem resistant; river; resistant enterobacterales; water ... See more keywords
Clinical characteristics and treatment outcomes of carbapenem-resistant Enterobacterales infections in Japan.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of global antimicrobial resistance"
DOI: 10.1016/j.jgar.2022.04.004
Abstract: OBJECTIVE The dissemination of difficult-to-treat carbapenem-resistant Enterobacterales (CRE) is of great concern. We clarified the risk factors underlying CRE infection mortality in Japan. METHODS We conducted a retrospective, multicentre, observational cohort study of patients with… read more here.
Keywords: treatment; carbapenem resistant; risk factors; mortality ... See more keywords
Poor outcomes in both infection and colonization with carbapenem-resistant Enterobacterales
Sign Up to like & getrecommendations! Published in 2022 at "Infection Control and Hospital Epidemiology"
DOI: 10.1017/ice.2022.4
Abstract: Abstract Objectives: To describe the epidemiology of patients with nonintestinal carbapenem-resistant Enterobacterales (CRE) colonization and to compare clinical outcomes of these patients to those with CRE infection. Design: A secondary analysis of Consortium on Resistance… read more here.
Keywords: resistant enterobacterales; carbapenem resistant; colonization; infection ... See more keywords
In vitro susceptibility of carbapenem resistant Enterobacterales to meropenem-vaborbactam and ceftazidime-avibactam at a single academic medical centre
Sign Up to like & getrecommendations! Published in 2023 at "Infectious Diseases"
DOI: 10.1080/23744235.2023.2177337
Abstract: Abstract Background Carbapenem-resistant Enterobacterales (CRE) are considered an urgent threat. Ceftazidime-avibactam and meropenem-vaborbactam contain β-lactamase inhibitors active against CRE isolates including those that produce Klebsiella pneumoniae carbapenemases (KPC). Methods Retrospective chart review of CRE isolates… read more here.
Keywords: carbapenem resistant; resistant enterobacterales; meropenem vaborbactam; ceftazidime avibactam ... See more keywords
Molecular Characterization of Carbapenem-Resistant Enterobacterales Collected in the United States.
Sign Up to like & getrecommendations! Published in 2022 at "Microbial drug resistance"
DOI: 10.1089/mdr.2021.0106
Abstract: Carbapenem-resistant Enterobacterales (CRE) are a growing public health concern due to resistance to multiple antibiotics and potential to cause health care-associated infections with high mortality. Carbapenemase-producing CRE are of particular concern given that carbapenemase-encoding genes… read more here.
Keywords: carbapenem resistant; carbapenem; carbapenemase producing; resistant enterobacterales ... See more keywords
Polymyxin B Activity Rescue by (-)-Camphene-Based Thiosemicarbazide Against Carbapenem-Resistant Enterobacterales.
Sign Up to like & getrecommendations! Published in 2022 at "Microbial drug resistance"
DOI: 10.1089/mdr.2021.0334
Abstract: Due to the significant shortage of therapeutic options for carbapenem-resistant Enterobacterales (CRE) infections, new drugs or therapeutic combinations are urgently required. We show in this study that (-)-camphene-based thiosemicarbazide (TSC) may act synergistically with polymyxin… read more here.
Keywords: carbapenem resistant; based thiosemicarbazide; activity; camphene based ... See more keywords
Acquisition of Enterobacterales carrying the colistin resistance gene mcr following travel to the tropics.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of travel medicine"
DOI: 10.1093/jtm/taac141
Abstract: BACKGROUND Colistin is an antibiotic of last resort in the management of highly drug-resistant Enterobacterales infections. Travel to some destinations presents a high risk of acquiring multidrug-resistant Enterobacterales, but little data are available on the… read more here.
Keywords: colistin resistant; colistin; resistance; following travel ... See more keywords
1621. Novel Beta-lactam Beta-lactamase Inhibitors Against Alternative Antibiotics for the Treatment of Complicated Urinary Tract Infections and Pyelonephritis Caused by Carbapenem-resistant Enterobacterales
Sign Up to like & getrecommendations! Published in 2020 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofaa439.1801
Abstract: There is little data on the comparative efficacy or safety of carbapenem-resistant Enterobacterales (CRE)-targeted beta-lactam beta-lactamase inhibitors (BL-BLI), including ceftazidime/avibactam (CZA) and meropenem/vaborbactam (MVB), versus alternative antibiotics for the treatment of CRE complicated urinary tract… read more here.
Keywords: resistant enterobacterales; treatment; group; beta ... See more keywords
Predicting Risk of Multidrug-Resistant Enterobacterales Infections Among People With HIV
Sign Up to like & getrecommendations! Published in 2022 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofac487
Abstract: Abstract Background Medically vulnerable individuals are at increased risk of acquiring multidrug-resistant Enterobacterales (MDR-E) infections. People with HIV (PWH) experience a greater burden of comorbidities and may be more susceptible to MDR-E due to HIV-specific… read more here.
Keywords: people hiv; machine learning; cd4 cell; risk ... See more keywords
Extended‐spectrum β‐lactamase‐producing and carbapenem‐resistant Enterobacterales bloodstream infection after solid organ transplantation: Recent trends in epidemiology and therapeutic approaches
Sign Up to like & getrecommendations! Published in 2022 at "Transplant Infectious Disease"
DOI: 10.1111/tid.13881
Abstract: Infections caused by multidrug‐resistant gram‐negative bacilli (MDR GNB), in particular extended‐spectrum β‐lactamase‐producing (ESBL‐E) and carbapenem‐resistant Enterobacterales (CRE), pose a major threat in solid organ transplantation (SOT). Outcome prediction and therapy are challenging due to the… read more here.
Keywords: resistant enterobacterales; carbapenem resistant; spectrum lactamase; lactamase producing ... See more keywords