Risk Factors for Isolation of Carbapenem-resistant Enterobacterales from Normally Sterile Sites and Urine.
Sign Up to like & getrecommendations! Published in 2021 at "American journal of infection control"
DOI: 10.1016/j.ajic.2021.12.007
Abstract: BACKGROUND Invasive infections caused by carbapenem-resistant Enterobacterales (CRE) are of significant concern in healthcare settings. We assessed risk factors for CRE culture from a sterile site (invasive infection) compared to isolation from urine in a… read more here.
Keywords: infection; risk factors; resistant enterobacterales; carbapenem resistant ... See more keywords
Occurrence and distribution of Carbapenem-resistant Enterobacterales and carbapenemase genes along a highly polluted hydrographic basin.
Sign Up to like & getrecommendations! Published in 2022 at "Environmental pollution"
DOI: 10.1016/j.envpol.2022.118958
Abstract: We determined the distribution and temporal variation of Carbapenem Resistant Enterobacterales (CRE), carbapenemase-encoding genes and other antibiotic resistance genes (ARGs) in a highly polluted river (Lis River; Portugal), also assessing the potential influence of water… read more here.
Keywords: carbapenem resistant; river; resistant enterobacterales; water ... See more keywords
Clinical characteristics and treatment outcomes of carbapenem-resistant Enterobacterales infections in Japan.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of global antimicrobial resistance"
DOI: 10.1016/j.jgar.2022.04.004
Abstract: OBJECTIVE The dissemination of difficult-to-treat carbapenem-resistant Enterobacterales (CRE) is of great concern. We clarified the risk factors underlying CRE infection mortality in Japan. METHODS We conducted a retrospective, multicentre, observational cohort study of patients with… read more here.
Keywords: treatment; carbapenem resistant; risk factors; mortality ... See more keywords
Poor outcomes in both infection and colonization with carbapenem-resistant Enterobacterales
Sign Up to like & getrecommendations! Published in 2022 at "Infection Control and Hospital Epidemiology"
DOI: 10.1017/ice.2022.4
Abstract: Abstract Objectives: To describe the epidemiology of patients with nonintestinal carbapenem-resistant Enterobacterales (CRE) colonization and to compare clinical outcomes of these patients to those with CRE infection. Design: A secondary analysis of Consortium on Resistance… read more here.
Keywords: resistant enterobacterales; carbapenem resistant; colonization; infection ... See more keywords
Leveraging multi-database linkages to assess racial and ethnic disparities among Carbapenem-resistant Enterobacterales cases in Tennessee, 2015–2019
Sign Up to like & getrecommendations! Published in 2024 at "Infection Control and Hospital Epidemiology"
DOI: 10.1017/ice.2024.86
Abstract: Abstract Background: Awareness of health disparities’ impact on clinical outcomes is increasing. However, public health’s ability to highlight these trends can be limited by data missingness, such as on race and ethnicity. To better understand… read more here.
Keywords: resistant enterobacterales; race ethnicity; race; racial ethnic ... See more keywords
Reviewing novel treatment options for carbapenem-resistant Enterobacterales
Sign Up to like & getrecommendations! Published in 2024 at "Expert Review of Anti-infective Therapy"
DOI: 10.1080/14787210.2024.2303028
Abstract: ABSTRACT Introduction Carbapenem resistant Enterobacterales (CRE) are a major threat to global health and hospital-onset CRE infections have risen during the COVID-19 pandemic. Novel antimicrobials are now available for the treatment of CRE infections. There… read more here.
Keywords: treatment; treatment options; resistant enterobacterales; cre infections ... See more keywords
In vitro susceptibility of carbapenem resistant Enterobacterales to meropenem-vaborbactam and ceftazidime-avibactam at a single academic medical centre
Sign Up to like & getrecommendations! Published in 2023 at "Infectious Diseases"
DOI: 10.1080/23744235.2023.2177337
Abstract: Abstract Background Carbapenem-resistant Enterobacterales (CRE) are considered an urgent threat. Ceftazidime-avibactam and meropenem-vaborbactam contain β-lactamase inhibitors active against CRE isolates including those that produce Klebsiella pneumoniae carbapenemases (KPC). Methods Retrospective chart review of CRE isolates… read more here.
Keywords: carbapenem resistant; resistant enterobacterales; meropenem vaborbactam; ceftazidime avibactam ... See more keywords
Molecular Characterization of Carbapenem-Resistant Enterobacterales Collected in the United States.
Sign Up to like & getrecommendations! Published in 2022 at "Microbial drug resistance"
DOI: 10.1089/mdr.2021.0106
Abstract: Carbapenem-resistant Enterobacterales (CRE) are a growing public health concern due to resistance to multiple antibiotics and potential to cause health care-associated infections with high mortality. Carbapenemase-producing CRE are of particular concern given that carbapenemase-encoding genes… read more here.
Keywords: carbapenem resistant; carbapenem; carbapenemase producing; resistant enterobacterales ... See more keywords
Polymyxin B Activity Rescue by (-)-Camphene-Based Thiosemicarbazide Against Carbapenem-Resistant Enterobacterales.
Sign Up to like & getrecommendations! Published in 2022 at "Microbial drug resistance"
DOI: 10.1089/mdr.2021.0334
Abstract: Due to the significant shortage of therapeutic options for carbapenem-resistant Enterobacterales (CRE) infections, new drugs or therapeutic combinations are urgently required. We show in this study that (-)-camphene-based thiosemicarbazide (TSC) may act synergistically with polymyxin… read more here.
Keywords: carbapenem resistant; based thiosemicarbazide; activity; camphene based ... See more keywords
Acquisition of Enterobacterales carrying the colistin resistance gene mcr following travel to the tropics.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of travel medicine"
DOI: 10.1093/jtm/taac141
Abstract: BACKGROUND Colistin is an antibiotic of last resort in the management of highly drug-resistant Enterobacterales infections. Travel to some destinations presents a high risk of acquiring multidrug-resistant Enterobacterales, but little data are available on the… read more here.
Keywords: colistin resistant; colistin; resistance; following travel ... See more keywords
1621. Novel Beta-lactam Beta-lactamase Inhibitors Against Alternative Antibiotics for the Treatment of Complicated Urinary Tract Infections and Pyelonephritis Caused by Carbapenem-resistant Enterobacterales
Sign Up to like & getrecommendations! Published in 2020 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofaa439.1801
Abstract: There is little data on the comparative efficacy or safety of carbapenem-resistant Enterobacterales (CRE)-targeted beta-lactam beta-lactamase inhibitors (BL-BLI), including ceftazidime/avibactam (CZA) and meropenem/vaborbactam (MVB), versus alternative antibiotics for the treatment of CRE complicated urinary tract… read more here.
Keywords: resistant enterobacterales; treatment; group; beta ... See more keywords