Salvaging lives in carbapenem-resistant Gram-negative osteoarticular and soft tissue infections: early compromises save lives
Sign Up to like & getrecommendations! Published in 2022 at "International Orthopaedics"
DOI: 10.1007/s00264-022-05342-z
Abstract: Incidence of carbapenem-resistant Gram-negative infections has risen alarmingly all across the globe, both in developed and developing countries alike. The purpose of this study was to assess whether challenges of life-threatening infections with very high… read more here.
Keywords: gram negative; soft tissue; carbapenem resistant; resistant gram ... See more keywords
Active surveillance culture program in asymptomatic patients as a strategy to control multidrug-resistant gram-negative organisms: What should be considered?
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the Formosan Medical Association = Taiwan yi zhi"
DOI: 10.1016/j.jfma.2019.08.015
Abstract: The increasing burden of multidrug-resistant gram-negative bacilli (MDR-GNB) infection has highlighted the urgent requirement for efficient prevention and control strategies. A routine active surveillance culture (ASC) program of asymptomatic carriers as part of an infection… read more here.
Keywords: active surveillance; gram negative; program; multidrug resistant ... See more keywords
A method to quantify viable carbapenem resistant gram-negative bacteria in treated and untreated wastewater.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of microbiological methods"
DOI: 10.1016/j.mimet.2020.106070
Abstract: Carbapenem resistance, particularly in Enterobacteriaceae, is an urgent threat to public health worldwide. Wastewater treatment plants are a critical control point for the spread of antimicrobial resistance into the environment yet, due in part to… read more here.
Keywords: viable carbapenem; supplemented media; wastewater; carbapenem resistant ... See more keywords
Colistin-based Treatment of Multidrug-resistant Gram-negative Bacterial Pulmonary Infections After Lung Transplantation.
Sign Up to like & getrecommendations! Published in 2019 at "Transplantation proceedings"
DOI: 10.1016/j.transproceed.2018.04.068
Abstract: BACKGROUND Lung transplantation (LT) is a viable option for a select group of patients with end-stage lung disease. However, infections are a major complication after LT, accounting for significant morbidity and mortality. Several germs may… read more here.
Keywords: colistin; treatment; lung transplantation; transplantation ... See more keywords
Epidemiology of resistant gram-negative bacteria in nursing homes.
Sign Up to like & getrecommendations! Published in 2023 at "Infection control and hospital epidemiology"
DOI: 10.1017/ice.2022.225
Abstract: BACKGROUND Resistant gram-negative bacteria (R-GNB) colonization in nursing home patients can cause clinical infection and intrafacility transmission. Limited data exist on the roles of age and function on R-GNB colonization. METHODS A secondary data analysis… read more here.
Keywords: nursing homes; colonization; gnb colonization; epidemiology ... See more keywords
Active screening and patient-placement and cohort-placement strategies to decrease carbapenem-resistant gram-negative bacilli colonization and infection in pediatric patients: A 5-year retrospective observational study in China.
Sign Up to like & getrecommendations! Published in 2023 at "Infection control and hospital epidemiology"
DOI: 10.1017/ice.2023.20
Abstract: Carbapenem-resistant gram-negative bacilli (CR-GNB) colonization screening was initiated across high-risk departments (PICU, NICU, neonatal wards, and hematology departments) in January 2017, and several CR-GNB cohort and patient-placement strategies were introduced throughout the hospital in January… read more here.
Keywords: carbapenem resistant; colonization; placement; infection ... See more keywords
Discovery of Macrolide Antibiotics Effective against Multi-Drug Resistant Gram-Negative Pathogens.
Sign Up to like & getrecommendations! Published in 2021 at "Accounts of chemical research"
DOI: 10.1021/acs.accounts.1c00020
Abstract: ConspectusMacrolides are among the most widely prescribed antibiotics, particularly for bacterial lung infections, due to their favorable safety, oral bioavailability, and spectrum of activity against Gram-positive pathogens such as Streptococcus pneumoniae, the most common cause… read more here.
Keywords: gram negative; gram; drug resistant; multi drug ... See more keywords
Identification of 5-(Aryl/Heteroaryl)amino-4-quinolones as Potent Membrane-Disrupting Agents to Combat Antibiotic-Resistant Gram-Positive Bacteria.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.2c01151
Abstract: Nosocomial infections caused by resistant Gram-positive organisms are on the rise, presumably due to a combination of factors including prolonged hospital exposure, increased use of invasive procedures, and pervasive antibiotic therapy. Although antibiotic stewardship and… read more here.
Keywords: gram; identification; positive bacteria; amino quinolones ... See more keywords
Multiantigenic Nanotoxoids for Antivirulence Vaccination against Antibiotic-Resistant Gram-Negative Bacteria.
Sign Up to like & getrecommendations! Published in 2019 at "Nano letters"
DOI: 10.1021/acs.nanolett.9b01844
Abstract: Infections caused by multidrug-resistant Gram-negative bacteria have emerged as a major threat to public health worldwide. The high mortality and prevalence, along with the slow pace of new antibiotic discovery, highlight the necessity for new… read more here.
Keywords: antivirulence; gram negative; negative bacteria; multiantigenic nanotoxoids ... See more keywords
Discovery of cationic nonribosomal peptides as Gram-negative antibiotics through global genome mining
Sign Up to like & getrecommendations! Published in 2018 at "Nature Communications"
DOI: 10.1038/s41467-018-05781-6
Abstract: The worldwide prevalence of infections caused by antibiotic-resistant Gram-negative bacteria poses a serious threat to public health due to the limited therapeutic alternatives. Cationic peptides represent a large family of antibiotics and have attracted interest… read more here.
Keywords: gram negative; gram; cationic nonribosomal; nonribosomal peptides ... See more keywords
Discrimination of antibiotic-resistant Gram-negative bacteria with a novel 3D nano sensing array.
Sign Up to like & getrecommendations! Published in 2020 at "Chemical communications"
DOI: 10.1039/c9cc09462h
Abstract: A novel sensor array based on a (+)AuNP/AuNC nanocomposite was constructed for the selective discrimination of 10 types of Gram-negative bacteria (including 3 types of antibiotic-resistant strains) at a low concentration level of OD600 =… read more here.
Keywords: gram negative; antibiotic resistant; negative bacteria; discrimination antibiotic ... See more keywords