Effect of zonisamide on refractory epilepsy during pregnancy in lamotrigine resistant kindled rats
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DOI: 10.1016/j.neulet.2017.11.020
Abstract: Drug-resistant epilepsy with uncontrolled severe seizures despite state-of-the-art medical treatment continues to be a major clinical problem. Pregnancy is a state where drug pharmacokinetic changes are more pronounced and more rapid than any other period… read more here.
Keywords: epilepsy; pregnancy; refractory epilepsy; epilepsy pregnancy ... See more keywords
Docosahexaenoic acid prevents resistance to antiepileptic drugs in two animal models of drug-resistant epilepsy
Sign Up to like & getrecommendations! Published in 2018 at "Nutritional Neuroscience"
DOI: 10.1080/1028415x.2017.1422903
Abstract: Objectives: One-third of epileptic patients are resistant to antiepileptic drugs. Few clinical studies with small sample size indicate that polyunsaturated fatty acids could control drug-resistant epilepsy. We examined the efficacy of acute and chronic administration… read more here.
Keywords: ltg; kindled rats; drug resistant; dha ... See more keywords