Essential Oils from Vitex agnus castus L. Leaves Induces Caspase-Dependent Apoptosis of Human Multidrug-Resistant Lung Carcinoma Cells through Intrinsic and Extrinsic Pathways
Sign Up to like & getrecommendations! Published in 2020 at "Nutrition and Cancer"
DOI: 10.1080/01635581.2020.1823439
Abstract: Abstract Essential oil (EO) fractions of plants are complex mixtures of volatile compounds with broad-spectrum biological properties. In the current study, the EO content of Vitex agnus castus L. (VAC) leaves growing in the Aegean… read more here.
Keywords: caspase; apoptosis; resistant lung; vitex agnus ... See more keywords
Trilobatin Induces Apoptosis and Attenuates Stemness Phenotype of Acquired Gefitinib Resistant Lung Cancer Cells via Suppression of NF-κB Pathway.
Sign Up to like & getrecommendations! Published in 2021 at "Nutrition and cancer"
DOI: 10.1080/01635581.2021.1912368
Abstract: Trilobatin is a common type of flavonoids compounds derived from Lithocarpus polystachyus Rehd leaves. Previous report suggests that trilobatin was potentially involved in pro-and anticancer, antioxidative and anti-hyperglycemic activities. Here, we investigated the anticancer efficiency… read more here.
Keywords: lung cancer; resistant lung; cancer cells; cancer ... See more keywords
Abstract 4361: Kynurenine - Aryl hydrocarbon receptor axis: A crucial modulator of immunometabolism in cisplatin resistant lung cancer
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Research"
DOI: 10.1158/1538-7445.sabcs18-4361
Abstract: The effect of tumor metabolism on the tumor microenvironment is not well established. Our previous data have shown that cisplatin resistant (CR) lung cancer cells increased secretion of thioredoxin-1 (TRX1) and kynurenine (KYN). Interestingly, high… read more here.
Keywords: kyn; resistant lung; cancer; cisplatin resistant ... See more keywords
Exploiting ROS and metabolic differences to kill cisplatin resistant lung cancer
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DOI: 10.18632/oncotarget.17568
Abstract: Cisplatin resistance remains a major problem in the treatment of lung cancer. We have discovered that cisplatin resistant (CR) lung cancer cells, regardless of the signaling pathway status, share the common parameter which is an… read more here.
Keywords: cisplatin resistant; cisplatin; resistant lung; lung cancer ... See more keywords
MicroRNA-128 suppresses paclitaxel-resistant lung cancer by inhibiting MUC1-C and BMI-1 in cancer stem cells
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DOI: 10.18632/oncotarget.22818
Abstract: The existence of cancer stem cells (CSCs) is the main reason for failure of cancer treatment caused by drug resistance. Therefore, eradicating cancers by targeting CSCs remains a significant challenge. In the present study, because… read more here.
Keywords: cancer stem; bmi; resistant lung; mir 128 ... See more keywords