Biochemical and genetic characterization of Botrytis cinerea laboratory mutants resistant to propamidine.
Sign Up to like & getrecommendations! Published in 2022 at "Pest management science"
DOI: 10.1002/ps.7150
Abstract: BACKGROUND Botrytis cinerea, the causal agent of gray mold, is one of the top ten fungal pathogens in the world. Propamidine, an aromatic diamidine compound, exhibited both protective and therapeutic effects against B. cinerea. However,… read more here.
Keywords: propamidine; botrytis cinerea; resistance; resistant mutants ... See more keywords
Sethoxydim-resistant mutants of the thermotolerant microalga Micractinium sp. accumulate significant amounts of triacylglycerol in non-stressful conditions
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Applied Phycology"
DOI: 10.1007/s10811-019-01859-w
Abstract: Because of their high lipid content, microalgae are regarded as a potentially competitive source for biofuels. However, one of the main biotechnological challenges in algae-based biofuels is that cell division is arrested under conditions which… read more here.
Keywords: mutants thermotolerant; sethoxydim resistant; mut; resistant mutants ... See more keywords
Enhancement of salinomycin production by ribosome engineering in Streptomyces albus
Sign Up to like & getrecommendations! Published in 2018 at "Science China Life Sciences"
DOI: 10.1007/s11427-018-9474-7
Abstract: Streptomyces can produce a large variety of secondary metabolites as a major source of anti-infective, antitumor or immune-suppressive agents widely applied in clinical treatment. Antibiotics-resistant bacteria are spreading at alarming rates. Natural active products and… read more here.
Keywords: ribosome engineering; gene; resistant mutants; production ... See more keywords
Isolation and characterization of spontaneous phage-resistant mutants of Lactobacillus paracasei
Sign Up to like & getrecommendations! Published in 2019 at "Food Control"
DOI: 10.1016/j.foodcont.2018.12.037
Abstract: Abstract Spontaneous phage-resistant mutants were isolated from Lactobacillus paracasei LPC by agar plate (AP) and secondary-culture (SC) methods. They were characterized by cell and colony morphologies, carbohydrate fermentation patterns, phage resistance stability, efficiency of plaquing… read more here.
Keywords: spontaneous phage; resistant mutants; isolation characterization; phage ... See more keywords
Molecular and biological characterization of Sclerotinia sclerotiorum resistant to the anilinopyrimidine fungicide cyprodinil.
Sign Up to like & getrecommendations! Published in 2018 at "Pesticide biochemistry and physiology"
DOI: 10.1016/j.pestbp.2018.03.001
Abstract: Cyprodinil belongs to the chemical class of anilinopyrimidines fungicides. In this study, baseline sensitivity of Sclerotinia sclerotiorum (Lib.) de Bary to cyprodinil was determined using 100 strains collected from the fields in Jiangsu Province of… read more here.
Keywords: sclerotinia sclerotiorum; sclerotiorum; cyprodinil; resistance ... See more keywords
The role of RND-type efflux pumps in multidrug-resistant mutants of Klebsiella pneumoniae
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DOI: 10.1038/s41598-020-67820-x
Abstract: The emergence of multidrug-resistant Klebsiella pneumoniae is a worldwide problem. K. pneumoniae possesses numerous resistant genes in its genome. We isolated mutants resistant to various antimicrobials in vitro and investigated the importance of intrinsic genes… read more here.
Keywords: rnd type; pneumoniae; resistant mutants; multidrug resistant ... See more keywords
Pervasive Selection for Clinically Relevant Resistance and Media Adaptive Mutations at Very Low Antibiotic Concentrations
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DOI: 10.1093/molbev/msad010
Abstract: Abstract Experimental evolution studies have shown that weak antibiotic selective pressures (i.e., when the antibiotic concentrations are far below the minimum inhibitory concentration, MIC) can select resistant mutants, raising several unanswered questions. First, what are… read more here.
Keywords: antibiotic concentrations; adaptive mutations; low antibiotic; resistance ... See more keywords
Evolution under low antibiotic concentrations: a risk for the selection of Pseudomonas aeruginosa multidrug-resistant mutants in nature.
Sign Up to like & getrecommendations! Published in 2021 at "Environmental microbiology"
DOI: 10.1111/1462-2920.15806
Abstract: Antibiotic pollution of non-clinical environments might have a relevant impact on human health if resistant pathogens are selected. However, this potential risk is often overlooked, since drug concentrations in nature are usually below their minimal… read more here.
Keywords: risk; pseudomonas aeruginosa; sub mic; mic selective ... See more keywords
Spatial structure facilitates the accumulation and persistence of antibiotic‐resistant mutants in biofilms
Sign Up to like & getrecommendations! Published in 2019 at "Evolutionary Applications"
DOI: 10.1111/eva.12728
Abstract: The emergence and spread of antibiotic resistance in bacterial pathogens are a global crisis. Because many bacterial infections are caused by pathogens that reside in biofilms, we sought to investigate how biofilms influence the evolution… read more here.
Keywords: facilitates accumulation; spatial structure; antibiotic resistant; resistant mutants ... See more keywords
Rapid and robust evolution of collateral sensitivity in Pseudomonas aeruginosa antibiotic-resistant mutants
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DOI: 10.1126/sciadv.aba5493
Abstract: Analysis of convergent collateral sensitivity phenotypes may guide the design of antibiotic therapies in P. aeruginosa infections. The analysis of trade-offs, as collateral sensitivity, associated with the acquisition of antibiotic resistance, is mainly based on… read more here.
Keywords: pseudomonas aeruginosa; collateral sensitivity; antibiotic resistant; sensitivity ... See more keywords
Increased Innate Immune Susceptibility in Hyperpigmented Bacteriophage-Resistant Mutants of Pseudomonas aeruginosa
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DOI: 10.1128/aac.00239-22
Abstract: Bacteriophage (phage) therapy is an alternative to traditional antibiotic treatments that is particularly important for multidrug-resistant pathogens, such as Pseudomonas aeruginosa. Unfortunately, phage resistance commonly arises during treatment as bacteria evolve to survive phage predation.… read more here.
Keywords: pseudomonas aeruginosa; phage resistant; phage therapy; bacteriophage ... See more keywords