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Published in 2023 at "JAMA ophthalmology"
DOI: 10.1001/jamaophthalmol.2023.1109
Abstract: This case report describes severe multidrug-resistant Pseudomonas aeruginosa keratitis in a 72-year-old man after EzriCare artificial tear use. read more here.
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Published in 2018 at "Journal of global antimicrobial resistance"
DOI: 10.1016/j.jgar.2018.01.010
Abstract: OBJECTIVES The incidence of infections caused by multidrug-resistant Pseudomonas aeruginosa (MDR-Pa) has become a concern of increasing relevance nowadays. Ceftolozane/tazobactam (C/T) is a novel fifth-generation cephalosporin/β-lactamase inhibitor combination with activity against MDR-Pa. METHODS The clinical… read more here.
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Published in 2018 at "Journal of global antimicrobial resistance"
DOI: 10.1016/j.jgar.2018.01.026
Abstract: OBJECTIVES The increasing incidence of carbapenem-resistant Pseudomonas aeruginosa along with the discovery of novel metallo-β-lactamases (MBLs) is of concern. In this study, the isolation of MBL-producing P. aeruginosa clinical strains in Malaysia was investigated. METHODS… read more here.
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Published in 2020 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.0c00114
Abstract: The decline of clinical effective antibiotics has made it necessary to develop more effective antimicrobial agents, especially for refractory biofilm-related infections. Silver nanoparticles (AgNPs) are a new type of antimicrobial agent that can eradicate biofilms… read more here.
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Published in 2023 at "Nature Communications"
DOI: 10.1101/2023.03.01.530582
Abstract: Rapid antibiotic resistance in bacteria is putting pressure on both existing therapies as well as the development pipeline. Here, the authors present a dual-acting anti-virulence treatment that evades antibiotic resistance mechanisms and remains effective against… read more here.
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Published in 2022 at "Letters in Applied Microbiology"
DOI: 10.1111/lam.13822
Abstract: The increasing prevalence of carbapenem‐resistant Pseudomonas aeruginosa (CRPA) strains in the hospital setting represents an emerging challenge to clinical treatment for Pseudomonas aeruginosa (PA) infections, as the range of therapeutic agents active against these pathogens… read more here.
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Published in 2023 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.00277-23
Abstract: Resistant Gram-negative bacteria are a growing concern in the United States, leading to significant morbidity and mortality. We identified a 72-year-old female patient who presented with unilateral vision loss. ABSTRACT Resistant Gram-negative bacteria are a… read more here.
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Published in 2023 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.01641-22
Abstract: The emergence of multidrug-resistant Pseudomonas aeruginosa infections has urged the need to find new strategies, such as the use of combinations of antibiotics. Among these, the combination of colistin with other antibiotics has been studied.… read more here.
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Published in 2019 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.01669-19
Abstract: The in vitro activity of WCK 5222 (cefepime-zidebactam) was compared to that of several available combination therapies among 30 clinical carbapenem-resistant Pseudomonas aeruginosa (CRP) strains using gradient diffusion strips. The combinations included nonsusceptible β-lactams (cefepime,… read more here.
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Published in 2022 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.02678-21
Abstract: Antibiotic resistance imposes a severe threat on human health. WCK 5222 is a β-lactam/β-lactamase inhibitor combination that is composed of cefepime and zidebactam. ABSTRACT WCK 5222 (cefepime/zidebactam) is a β-lactam/β-lactamase inhibitor combination that is effective… read more here.
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Published in 2018 at "Revista da Sociedade Brasileira de Medicina Tropical"
DOI: 10.1590/0037-8682-0506-2017
Abstract: Pseudomonas aeruginosa is the leading cause of nosocomial infections with high mortality rates owing to the limited therapeutic options for multidrug-resistant Pseudomonas aeruginosa (MDRPA) and metallo-beta-lactamase (MBL)-producing strains. Herein, we present a meta-analysis exploring the… read more here.