Molecular characterisation of aromatase inhibitor-resistant advanced breast cancer: the phenotypic effect of ESR1 mutations
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DOI: 10.1038/s41416-018-0345-x
Abstract: BackgroundSeveral thousand breast cancer patients develop resistance to aromatase inhibitors (AIs) each year in the UK. Rational treatment requires an improved molecular characterisation of resistant disease.Materials and methodsThe mutational landscape of 198 regions in 16… read more here.
Keywords: molecular characterisation; breast cancer; resistant tumours; cancer ... See more keywords