A substitution/dynamic kinetic resolution – Asymmetric transfer hydrogenation tandem process for preparation of stereocenters β-hydroxy sulfones
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Catalysis"
DOI: 10.1016/j.mcat.2018.04.019
Abstract: Abstract A noval method for the synthesis of optically active β-hydroxy sulfones was developed. Through a substitution/dynamic kinetic resolution–asymmetric transfer hydrogenation, the presented method was based on one-pot enantioselective organic transformations of α–bromoindenones and sodium… read more here.
Keywords: resolution asymmetric; hydroxy sulfones; kinetic resolution; dynamic kinetic ... See more keywords
Efficient kinetic resolution in the asymmetric transfer hydrogenation of 3-aryl-indanones: applications to a short synthesis of (+)-indatraline and a formal synthesis of (R)-tolterodine
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DOI: 10.1039/d1ra04538e
Abstract: Efficient kinetic resolution occurs in ATH of racemic 3-arylindanones using (R,R)-or (S,S)-Ts-DENEB catalyst and HCO2H/Et3N mixture providing near equal yields of cis-3-arylindanols and unreacted 3-arylindanones with excellent stereoselectivities. read more here.
Keywords: resolution asymmetric; kinetic resolution; asymmetric transfer; efficient kinetic ... See more keywords