Super Resolution Cryo-EM Maps with 3D Deep Generative Networks
Sign Up to like & getrecommendations! Published in 2021 at "Biophysical Journal"
DOI: 10.1016/j.bpj.2020.11.1801
Abstract: An increasing number of biological macromolecules have been solved with cryo-electron microscopy (cryo-EM). Over the past few years, the resolutions of density maps determined by cryo-EM have largely improved in general. However, there are still… read more here.
Keywords: resolution; super resolution; cryo; resolution cryo ... See more keywords
A 3.8 Å resolution cryo-EM structure of a small protein bound to an imaging scaffold
Sign Up to like & getrecommendations! Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-019-09836-0
Abstract: Proteins smaller than about 50 kDa are currently too small to be imaged at high resolution by cryo-electron microscopy (cryo-EM), leaving most protein molecules in the cell beyond the reach of this powerful structural technique. Here… read more here.
Keywords: protein; cryo structure; microscopy; resolution cryo ... See more keywords
Mechanism of actin filament branch formation by Arp2/3 complex revealed by a high-resolution cryo-EM structureof the branch junction
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2206722119
Abstract: Significance Arp2/3 complex is a protein assembly with seven subunits that forms actin filament branches on the sides of preexisting “mother” actin filaments. This process generates growing actin filaments for cellular locomotion and intracellular movements.… read more here.
Keywords: resolution cryo; branch; actin filament; arp2 complex ... See more keywords
High-resolution cryo-EM structures of plant cytochrome b6f at work
Sign Up to like & getrecommendations! Published in 2023 at "Science Advances"
DOI: 10.1126/sciadv.add9688
Abstract: Plants use solar energy to power cellular metabolism. The oxidation of plastoquinol and reduction of plastocyanin by cytochrome b6f (Cyt b6f) is known as one of the key steps of photosynthesis, but the catalytic mechanism… read more here.
Keywords: resolution cryo; cryo structures; cytochrome b6f; high resolution ... See more keywords