Combined magnetic ligand fishing and high-resolution inhibition profiling for identification of α-glucosidase inhibitory ligands: A new screening approach based on complementary inhibition and affinity profiles.
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DOI: 10.1016/j.talanta.2019.03.047
Abstract: Plants are well-recognized sources of inhibitors for α-glucosidase - a key target enzyme for management of type 2 diabetes. Recently, two advanced bioactivity-profiling techniques, i.e., ligand fishing and high-resolution inhibition profiling, have shown great promises… read more here.
Keywords: resolution inhibition; high resolution; fishing high; inhibition profiling ... See more keywords