E-type prostanoid receptor 4 drives resolution of intestinal inflammation by blocking epithelial necroptosis
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DOI: 10.1038/s41556-021-00708-8
Abstract: Inflammatory bowel diseases present with elevated levels of intestinal epithelial cell (IEC) death, which compromises the gut barrier, activating immune cells and triggering more IEC death. The endogenous signals that prevent IEC death and break… read more here.
Keywords: prostanoid receptor; resolution intestinal; intestinal inflammation; necroptosis ... See more keywords
Single-cell resolution of intestinal regeneration in pythons without crypts illuminates conserved vertebrate regenerative mechanisms
Sign Up to like & getrecommendations! Published in 2024 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2405463121
Abstract: Significance The vertebrate intestine is well known for its regenerative capacity, but existing research emphasizes the role of a crypt–villus axis in the constant turnover of the intestinal epithelium. Mechanisms that support large-scale intestinal regeneration… read more here.
Keywords: single cell; cell resolution; intestinal regeneration; resolution intestinal ... See more keywords