Application of 2D EXSY and qNMR Spectroscopy for Diastereomeric Excess Determination Following Chiral Resolution of β‐Lactams
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DOI: 10.1002/open.202200119
Abstract: Abstract Trans‐β‐lactam isomers have garnered much attention as anti‐cancer microtubule targeting agents. Currently available synthetic methods are available for the preparation of enantiopure β‐lactams and favour isomeric cis/trans β‐lactam mixtures. Indirect chiral resolution offers the… read more here.
Keywords: spectroscopy; chiral resolution; resolution lactams; resolution ... See more keywords