Towards the Next Generation of Data‐Driven Therapeutics Using Spatially Resolved Single‐Cell Technologies and Generative AI
Sign Up to like & getrecommendations! Published in 2025 at "European Journal of Immunology"
DOI: 10.1002/eji.202451234
Abstract: Recent advances in multi‐omics and spatially resolved single‐cell technologies have revolutionised our ability to profile millions of cellular states, offering unprecedented opportunities to understand the complex molecular landscapes of human tissues in both health and… read more here.
Keywords: spatially resolved; single cell; cell technologies; cell ... See more keywords
Frontiers in Single-Crystal Covalent Organic Framework Resolved by Single Crystal X-ray Diffraction
Sign Up to like & getrecommendations! Published in 2025 at "Inorganic Chemistry Frontiers"
DOI: 10.1039/d5qi01802a
Abstract: The design of covalent organic frameworks (COFs) in single-crystal forms with definite structures that can be resolved by single crystal X-ray diffraction (SCXRD) is a key foundation for their further... read more here.
Keywords: crystal; resolved single; covalent organic; ray diffraction ... See more keywords
The potential and challenges of time-resolved single-photon detection based on current-carrying superconducting nanowires
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Physics D: Applied Physics"
DOI: 10.1088/1361-6463/ab4146
Abstract: Superconducting nanowire-based devices are being hailed as promising single photon detectors that could exhibit excellent combined properties. In particular, their unrivalled time-resolution ability has made these devices potentially revolutionary for the commercial ultrafast single photon… read more here.
Keywords: resolved single; photon detection; time; time resolved ... See more keywords
Spatially-resolved single-cell assessment of pancreatic cancer expression subtypes reveals co-expressor phenotypes and extensive intra-tumoral heterogeneity.
Sign Up to like & getrecommendations! Published in 2022 at "Cancer research"
DOI: 10.1158/0008-5472.can-22-3050
Abstract: Pancreatic ductal adenocarcinoma (PDAC) has been classified into classical and basal-like transcriptional subtypes by bulk RNA measurements. However, recent work has uncovered greater complexity to transcriptional subtypes than was initially appreciated using bulk RNA expression… read more here.
Keywords: intra tumoral; cell; heterogeneity; expression ... See more keywords