Backbone 1H, 15N, and 13C resonance assignments of the Tom1 VHS domain
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DOI: 10.1007/s12104-016-9709-4
Abstract: Efficient trafficking of ubiquitinated receptors (cargo) to endosomes requires the recruitment of adaptor proteins that exhibit ubiquitin-binding domains for recognition and transport. Tom1 is an adaptor protein that not only associates with ubiquitinated cargo but… read more here.
Keywords: assignments tom1; resonance assignments; tom1 vhs; vhs domain ... See more keywords
Backbone resonance assignments of monomeric SOD1 in dilute and crowded environments
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DOI: 10.1007/s12104-016-9724-5
Abstract: Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease that leads to movement disorders. In motor neurons of ALS patients, intracellular aggregates of superoxide dismutase 1 (SOD1) have often been observed. To elucidate the aggregation… read more here.
Keywords: protein; backbone resonance; sod1; monomeric sod1 ... See more keywords
Backbone resonance assignments for the SET domain of human methyltransferase NSD3 in complex with its cofactor
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DOI: 10.1007/s12104-017-9753-8
Abstract: NSD3 is a histone H3 methyltransferase that plays an important role in chromatin biology. A construct containing the methyltransferase domain encompassing residues Q1049-K1299 of human NSD3 was obtained and biochemical activity was demonstrated using histone… read more here.
Keywords: backbone resonance; resonance assignments; methyltransferase; nsd3 ... See more keywords
Backbone and side-chain 1H, 15N, and 13C resonance assignments of a novel Staphylococcal inhibitor of myeloperoxidase
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DOI: 10.1007/s12104-017-9764-5
Abstract: The bacterium Staphylococcus aureus produces an array of anti-inflammatory molecules that prevent the innate immune system from recognizing it as a pathogen and clearing it from the host. In the acute phase of inflammation, our… read more here.
Keywords: chain 15n; resonance assignments; side chain; backbone side ... See more keywords
NMR resonance assignments of the NZF domain of mouse HOIL-1L free and bound to linear di-ubiquitin
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DOI: 10.1007/s12104-018-09868-5
Abstract: Nuclear factor-κB (NF-κB) activation plays a central role in immunity and inflammation. In the canonical NF-κB activation pathway, linear polyubiquitin chains conjugated by the linear ubiquitin chain assembly complex (LUBAC) are specifically recognized by the Npl4… read more here.
Keywords: assignments nzf; resonance assignments; nzf domain; linear ubiquitin ... See more keywords
Backbone resonance assignments and secondary structure of Ebola nucleoprotein 600–739 construct
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DOI: 10.1007/s12104-019-09898-7
Abstract: Ebola viral infections have resulted in several deadly epidemics in recent years in West and Central Africa. Because only one of the seven proteins encoded by the viral genome possesses enzymatic activity, disruption of protein–protein… read more here.
Keywords: backbone resonance; resonance assignments; secondary structure; 600 739 ... See more keywords