Assessing Brain Metabolism With 7-T Proton Magnetic Resonance Spectroscopy in Patients With First-Episode Psychosis
Sign Up to like & getrecommendations! Published in 2019 at "JAMA Psychiatry"
DOI: 10.1001/jamapsychiatry.2018.3637
Abstract: Importance The use of high-field magnetic resonance spectroscopy (MRS) in multiple brain regions of a large population of human participants facilitates in vivo study of localized or diffusely altered brain metabolites in patients with first-episode… read more here.
Keywords: resonance spectroscopy; magnetic resonance; first episode; patients first ... See more keywords
Chiral analysis of pantolactone with molecular rotational resonance spectroscopy.
Sign Up to like & getrecommendations! Published in 2021 at "Chirality"
DOI: 10.1002/chir.23379
Abstract: A molecular rotational resonance spectroscopy method for measuring the enantiomeric excess of pantolactone, an intermediate in the synthesis of panthenol and pantothenic acid, is presented. The enantiomers are distinguished via complexation with a small chiral… read more here.
Keywords: resonance spectroscopy; pantolactone; analysis; rotational resonance ... See more keywords
Evidence for inefficient contraction and abnormal mitochondrial activity in sarcopenia using magnetic resonance spectroscopy
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Cachexia, Sarcopenia and Muscle"
DOI: 10.1002/jcsm.13220
Abstract: Mitochondrial dysfunction has been implicated in sarcopenia. 31P magnetic resonance spectroscopy (MRS) enables non‐invasive measurement of adenosine triphosphate (ATP) synthesis rates to probe mitochondrial function. Here, we assessed muscle energetics in older sarcopenic and non‐sarcopenic… read more here.
Keywords: magnetic resonance; resonance spectroscopy; spectroscopy; evidence inefficient ... See more keywords
Comparing the reproducibility of commonly used magnetic resonance spectroscopy techniques to quantify cerebral glutathione
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Magnetic Resonance Imaging"
DOI: 10.1002/jmri.26046
Abstract: Cerebral glutathione (GSH), a marker of oxidative stress, has been quantified in neurodegenerative diseases and psychiatric disorders using proton magnetic resonance spectroscopy (MRS). Using a reproducible MRS technique is important, as it minimizes the impact… read more here.
Keywords: resonance spectroscopy; cerebral glutathione; magnetic resonance; spectroscopy ... See more keywords
Repeatability and reliability of GABA measurements with magnetic resonance spectroscopy in healthy young adults
Sign Up to like & getrecommendations! Published in 2020 at "Magnetic Resonance in Medicine"
DOI: 10.1002/mrm.28587
Abstract: Gamma‐aminobutyric acid (GABA) abnormalities have been implicated in a range of neuropsychiatric disorders. Despite substantial interest in probing GABA in vivo, human imaging studies relying on magnetic resonance spectroscopy (MRS) have generally been hindered by… read more here.
Keywords: resonance spectroscopy; magnetic resonance; repeatability reliability; gaba ... See more keywords
Hyperpolarized 13C magnetic resonance spectroscopy detects toxin‐induced neuroinflammation in mice
Sign Up to like & getrecommendations! Published in 2019 at "NMR in Biomedicine"
DOI: 10.1002/nbm.4164
Abstract: Lipopolysaccharide (LPS) is a commonly used agent for induction of neuroinflammation in preclinical studies. Upon injection, LPS causes activation of microglia and astrocytes, whose metabolism alters to favor glycolysis. Assessing in vivo neuroinflammation and its… read more here.
Keywords: resonance spectroscopy; magnetic resonance; neuroinflammation; hyperpolarized 13c ... See more keywords
Cancer insights from magnetic resonance spectroscopy of cells and excised tumors
Sign Up to like & getrecommendations! Published in 2022 at "NMR in Biomedicine"
DOI: 10.1002/nbm.4724
Abstract: Multinuclear ex vivo magnetic resonance spectroscopy (MRS) of cancer cells, xenografts, human cancer tissue, and biofluids is a rapidly expanding field that is providing unique insights into cancer. Starting from the 1970s, the field has… read more here.
Keywords: magnetic resonance; resonance spectroscopy; spectroscopy; vivo mrs ... See more keywords
Magnetic Resonance Spectroscopy in neurodegenerative dementias, prodromal syndromes and at-risk states: a systematic review of the literature.
Sign Up to like & getrecommendations! Published in 2023 at "NMR in biomedicine"
DOI: 10.1002/nbm.4896
Abstract: BACKGROUND In recent years, magnetic resonance spectroscopy (MRS) has benefited from increased MRI field strengths, new acquisition protocols, and new processing techniques. This review aims to determine how this has altered our understanding of MRS… read more here.
Keywords: magnetic resonance; resonance spectroscopy; review; spectroscopy ... See more keywords
Neurochemical correlations in short echo time proton magnetic resonance spectroscopy.
Sign Up to like & getrecommendations! Published in 2023 at "NMR in biomedicine"
DOI: 10.1002/nbm.4910
Abstract: Neurochemical concentrations determined by magnetic resonance spectroscopy (MRS) have been treated as statistically independent measurements in various clinical MRS studies. However, spectral overlap, independent of any biological effects, could lead to significant correlations between neurochemical… read more here.
Keywords: magnetic resonance; resonance spectroscopy; spectroscopy; short echo ... See more keywords
Tumor Microenvironment Biosensors for Hyperpolarized Carbon-13 Magnetic Resonance Spectroscopy
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Imaging and Biology"
DOI: 10.1007/s11307-020-01570-0
Abstract: Hyperpolarization (HP) of a carbon-13 molecule via dynamic nuclear polarization (DNP) involves polarization at low temperature, followed by a dissolution procedure producing a solution with highly polarized spins at room temperature. This dissolution DNP method… read more here.
Keywords: resonance spectroscopy; microenvironment; magnetic resonance; spectroscopy ... See more keywords
Proton magnetic resonance spectroscopy in substance use disorder: recent advances and future clinical applications
Sign Up to like & getrecommendations! Published in 2020 at "Science China Information Sciences"
DOI: 10.1007/s11432-019-2818-5
Abstract: Proton magnetic resonance spectroscopy (1H-MRS) now is widely used in clinical researches for the measurement of compounds or metabolites in vivo, especially in neuropsychiatric diseases/disorders. Recently, there are many studies on substance use disorders utilizing… read more here.
Keywords: resonance spectroscopy; substance; substance use; magnetic resonance ... See more keywords