Respiratory Cilia as a Therapeutic Target of Phosphodiesterase Inhibitors
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2020.00609
Abstract: Mucociliary clearance is an essential airway defense mechanism dependent predominantly on the proper ciliary function and mucus rheology. The crucial role of cilia is evident in `a variety of respiratory diseases, as the ciliary dysfunction… read more here.
Keywords: pde inhibitors; phosphodiesterase; cilia therapeutic; function ... See more keywords
The effects of acute hydrogen peroxide exposure on respiratory cilia motility and viability
Sign Up to like & getrecommendations! Published in 2023 at "PeerJ"
DOI: 10.7717/peerj.14899
Abstract: COVID-19 has seen the propagation of alternative remedies to treat respiratory disease, such as nebulization of hydrogen peroxide (H2O2). As H2O2 has known cytotoxicity, it was hypothesised that H2O2 inhalation would negatively impact respiratory cilia… read more here.
Keywords: cilia motility; motility; respiratory cilia; h2o2 ... See more keywords