The respiratory depressant effects of mitragynine are limited by its conversion to 7‐OH mitragynine
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DOI: 10.1111/bph.15832
Abstract: Mitragynine, the major alkaloid in Mitragyna speciosa (kratom), is a partial agonist at the μ opioid receptor. CYP3A‐dependent oxidation of mitragynine yields the metabolite 7‐OH mitragynine, a more efficacious μ receptor agonist. While both mitragynine… read more here.
Keywords: respiratory depressant; depressant effects; mitragynine limited; mitragynine ... See more keywords