Early development of respiratory motor circuits in larval zebrafish (Danio rerio)
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Comparative Neurology"
DOI: 10.1002/cne.25467
Abstract: Rhythm‐generating circuits in the vertebrate hindbrain form synaptic connections with cranial and spinal motor neurons, to generate coordinated, patterned respiratory behaviors. Zebrafish provide a uniquely tractable model system to investigate the earliest stages in respiratory… read more here.
Keywords: development; respiratory motor; motor; pattern ... See more keywords
Coordinated cadherin functions sculpt respiratory motor circuit connectivity
Sign Up to like & getrecommendations! Published in 2022 at "eLife"
DOI: 10.1101/2022.08.02.502511
Abstract: Breathing, and the motor circuits that control it, are essential for life. At the core of respiratory circuits are Dbx1-derived interneurons, which generate the rhythm and pattern of breathing, and phrenic motor neurons (MNs), which… read more here.
Keywords: circuit; respiratory motor; motor; coordinated cadherin ... See more keywords
IL-1 receptor activation undermines respiratory motor plasticity after systemic inflammation.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of applied physiology"
DOI: 10.1152/japplphysiol.01051.2017
Abstract: Inflammation undermines respiratory motor plasticity, yet we are just beginning to understand the inflammatory signaling involved. Because interleukin-1 (IL-1) signaling promotes or inhibits plasticity in other central nervous system regions, we tested the following hypotheses:… read more here.
Keywords: respiratory motor; motor plasticity; plasticity; systemic inflammation ... See more keywords
Impact of Sleep Deprivation on Respiratory Motor Output and Endurance: A Physiological Study.
Sign Up to like & getrecommendations! Published in 2019 at "American journal of respiratory and critical care medicine"
DOI: 10.1164/rccm.201904-0819oc
Abstract: RATIONALE While sleep deprivation can alter endurance of skeletal muscles, its impact on respiratory command is unknown. We aimed to assess the effect of sleep deprivation on respiratory motor output and inspiratory endurance. METHODS Inspiratory… read more here.
Keywords: motor; sleep deprivation; motor output; respiratory motor ... See more keywords
Mu-opioid receptor-dependent transformation of respiratory motor pattern in neonates in vitro
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2022.921466
Abstract: Endogenous opioid peptides activating mu-opioid receptors (MORs) are part of an intricate neuromodulatory system that coordinates and optimizes respiratory motor output to maintain blood-gas homeostasis. MOR activation is typically associated with respiratory depression but also… read more here.
Keywords: burst amplitude; respiratory motor; motor; mor activation ... See more keywords