Cardiovascular and respiratory safety evaluation of Musca Domestica larvae low molecular weight peptide in beagle dogs
Sign Up to like & getrecommendations! Published in 2019 at "Toxicology Mechanisms and Methods"
DOI: 10.1080/15376516.2018.1519863
Abstract: Abstract Background: Many studies have demonstrated that the water extracts and low-molecular-weight peptide (LMWP) of the Musca domestica larvae contain significant biological activity. However, the cardiovascular and respiratory safety evaluations of LMWP are yet to… read more here.
Keywords: respiratory safety; domestica larvae; beagle dogs; respiratory ... See more keywords
Respiratory safety of lemborexant in healthy adult and elderly subjects with mild obstructive sleep apnea: A randomized, double‐blind, placebo‐controlled, crossover study
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Sleep Research"
DOI: 10.1111/jsr.13021
Abstract: Lemborexant is a dual orexin receptor antagonist indicated for the treatment of adult and elderly individuals with insomnia. Some current pharmacologic treatments for insomnia cause respiratory depression, a serious safety concern, particularly for individuals with… read more here.
Keywords: respiratory safety; lsm difference; treatment; placebo ... See more keywords