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Published in 2019 at "Lung"
DOI: 10.1007/s00408-019-00263-y
Abstract: Matrix metalloproteinase-12 (MMP-12) and Tissue inhibitor of metalloproteinase-4 (TIMP-4) play important roles in the pathophysiology of chronic obstructive pulmonary disease (COPD). Subjects of many previous studies were patients with severe and very severe COPD. However,…
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Keywords:
aecopd;
different respiratory;
aecopd patients;
timp ... See more keywords
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Published in 2021 at "Current Medical Science"
DOI: 10.1007/s11596-021-2316-3
Abstract: Positive nucleic acid (NA) results have been found in recovered and discharged COVID-19 patients, but the proportion is unclear. This study was designed to analyze the recurrent positive rate of NA results after consecutively negative…
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Keywords:
covid patients;
viral shedding;
564 covid;
specific antibodies ... See more keywords
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Published in 2021 at "Clinical Microbiology and Infection"
DOI: 10.1016/j.cmi.2021.02.014
Abstract: Objectives This study compares the infectivity of SARS-CoV-2 in respiratory samples from patients with mild COVID-19 with those from hospitalised patients with severe bilateral pneumonia. In severe COVID-19, we also analysed the presence of neutralising…
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Keywords:
patients severe;
sars cov;
respiratory samples;
severe covid ... See more keywords
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Published in 2021 at "Journal of Critical Care"
DOI: 10.1016/j.jcrc.2021.04.010
Abstract: Background Prolonged viral RNA detection in respiratory samples from patients with COVID-19 has been described, but the clinical relevance remains unclear. We studied the dynamics of SARS-CoV-2 on a group and individual level in intubated…
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Keywords:
viral load;
patients covid;
sars cov;
respiratory samples ... See more keywords
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Published in 2018 at "Practical Laboratory Medicine"
DOI: 10.1016/j.plabm.2018.e00102
Abstract: The aim of this study was to develop a multiplex PCR test to detect Achromobacter xylosoxidans (AX), Burkholderia cepacia (BC), Pseudomonas aeruginosa (PSA) and Stenotrophomonas maltophilia (SM) directly from CF patient's respiratory samples using the…
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Keywords:
max system;
pcr;
patient respiratory;
respiratory ... See more keywords
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Published in 2018 at "COPD: Journal of Chronic Obstructive Pulmonary Disease"
DOI: 10.1080/15412555.2017.1416074
Abstract: ABSTRACT IL-6 and IL-33 are involved in the inflammatory process in obstructive lung diseases. In contrast to IL-6, few data on the expression of IL-33 in different biological samples from asthma and COPD patients are…
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Keywords:
moderate asthma;
asthma copd;
copd;
respiratory samples ... See more keywords
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Published in 2017 at "Journal of Clinical Microbiology"
DOI: 10.1128/jcm.02483-16
Abstract: ABSTRACT Routine full characterization of Mycobacterium tuberculosis is culture based, taking many weeks. Whole-genome sequencing (WGS) can generate antibiotic susceptibility profiles to inform treatment, augmented with strain information for global surveillance; such data could be…
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Keywords:
whole genome;
dna;
tuberculosis;
genome sequencing ... See more keywords
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Published in 2020 at "Annals of Intensive Care"
DOI: 10.1186/s13613-020-00754-9
Abstract: Background Empirical antimicrobial therapy (EAT) is a challenge for community-acquired, hospital-acquired and ventilator-associated pneumonia, particularly in the context of the increasing occurrence of third-generation cephalosporin-resistant Enterobacterales (3GCR-E), including extended-spectrum beta-lactamase Enterobacterales (ESBL-E) and high-level expressed…
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Keywords:
screening;
intestinal carriage;
hlac;
respiratory samples ... See more keywords
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Published in 2023 at "Journal of Fungi"
DOI: 10.3390/jof9040414
Abstract: Pneumocystis jirovecii pneumonia (PJP) in immunocompromised patients entails high mortality and requires adequate laboratory diagnosis. We compared the performance of a real time-PCR assay against the immunofluorescence assay (IFA) in the routine of a large…
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Keywords:
jirovecii pneumonia;
respiratory samples;
pneumocystis jirovecii;
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Published in 2021 at "Viruses"
DOI: 10.3390/v13050801
Abstract: The availability of simple SARS-CoV-2 detection methods is crucial to contain the COVID-19 pandemic. This study examined whether a commercial LAMP assay can reliably detect SARS-CoV-2 genomes directly in respiratory samples without having to extract…
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Keywords:
lamp;
fast detection;
directly respiratory;
sars cov ... See more keywords