Lifetime imaging of GFP at CoxVIIIa reports respiratory supercomplex assembly in live cells
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep46055
Abstract: The assembly of respiratory complexes into macromolecular supercomplexes is currently a hot topic, especially in the context of newly available structural details. However, most work to date has been done with purified detergent-solubilized material and… read more here.
Keywords: respiratory supercomplex; coxviiia; lifetime imaging; gfp coxviiia ... See more keywords
Structure of mycobacterial CIII2CIV2 respiratory supercomplex bound to the tuberculosis drug candidate telacebec (Q203)
Sign Up to like & getrecommendations! Published in 2021 at "eLife"
DOI: 10.7554/elife.71959
Abstract: The imidazopyridine telacebec, also known as Q203, is one of only a few new classes of compounds in more than 50 years with demonstrated antituberculosis activity in humans. Telacebec inhibits the mycobacterial respiratory supercomplex composed… read more here.
Keywords: telacebec; mycobacterial ciii2civ2; structure mycobacterial; ciii2civ2 ... See more keywords