Identifying responders versus non‐responders: Incorporation of controls is required for sound statistical inference
Sign Up to like & getrecommendations! Published in 2020 at "Experimental Physiology"
DOI: 10.1113/ep089142
Abstract: In human physiology research, response variance is often anticipated and addressed in sample size planning. This planned approach is intended to provide due consideration of variation when seeking to detect a targeted net mean effect… read more here.
Keywords: response; responders versus; versus non; non responders ... See more keywords
Host-specific differences in top-expanded TCR clonotypes correlate with divergent outcomes of anti-PD-L1 treatment in responders versus non-responders
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1100520
Abstract: Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment; however, the responses to ICI treatment are highly variable in different individuals and the underlying mechanisms remain poorly understood. Here, we employed a mouse squamous cell carcinoma… read more here.
Keywords: tcr; tcr clonotypes; versus non; top expanded ... See more keywords