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   Articles with "response" as a keyword



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Phototherapy for Vitiligo: A Systematic Review and Meta-analysis

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recommendations! Published in 2017 at "JAMA Dermatology"

DOI: 10.1001/jamadermatol.2017.0002

Abstract: Importance References to the expected treatment response to phototherapy would be helpful in the management of vitiligo because phototherapy requires long treatment durations over several months. Objective To estimate the treatment response of vitiligo to… read more here.

Keywords: studies months; vitiligo; response; analysis ... See more keywords
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Assessment of Response to B-Cell Depletion Using Rituximab in Cutaneous Lupus Erythematosus

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recommendations! Published in 2018 at "JAMA Dermatology"

DOI: 10.1001/jamadermatol.2018.3793

Abstract: Importance Cutaneous lupus erythematosus (CLE) can be severe and treatment resistant. B-cell depletion therapy (BCDT) with rituximab is well recognized in organ involvement in systemic lupus erythematosus (SLE), but its efficacy in cutaneous manifestations is… read more here.

Keywords: cell depletion; response; lupus erythematosus; bilag grade ... See more keywords
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Treatment Outcomes of Topical Calcineurin Inhibitor Therapy for Patients With Vitiligo: A Systematic Review and Meta-analysis.

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recommendations! Published in 2019 at "JAMA dermatology"

DOI: 10.1001/jamadermatol.2019.0696

Abstract: Importance Topical calcineurin inhibitors (TCIs), including tacrolimus and pimecrolimus, have been widely used for the treatment of vitiligo; however, the efficacy of TCI monotherapy is often underestimated. Objectives To estimate the treatment responses to both… read more here.

Keywords: response; treatment; study; tci monotherapy ... See more keywords
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Circulating Brodalumab Levels and Therapy Outcomes in Patients With Psoriasis Treated With Brodalumab: A Case Series.

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recommendations! Published in 2022 at "JAMA dermatology"

DOI: 10.1001/jamadermatol.2022.1863

Abstract: Importance Given the possible treatment modalities in psoriasis management, little is known about whether drug monitoring is associated with response rate. Objective To determine whether drug monitoring is associated with response to brodalumab therapy. Design… read more here.

Keywords: patients psoriasis; case series; circulating brodalumab; therapy ... See more keywords
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Cost-effectiveness of Response-Adapted De-escalation of Immunotherapy in Advanced Melanoma.

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recommendations! Published in 2022 at "JAMA dermatology"

DOI: 10.1001/jamadermatol.2022.4556

Abstract: Importance Combination immunotherapy with nivolumab and ipilimumab has markedly improved outcomes for patients with advanced melanoma. However, these therapies pose a considerable financial burden to both patients and the health care system. The ADAPT-IT trial… read more here.

Keywords: advanced melanoma; cost; response adapted; response ... See more keywords
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Association of Serum Dupilumab Levels at 16 Weeks With Treatment Response and Adverse Effects in Patients With Atopic Dermatitis: A Prospective Clinical Cohort Study From the BioDay Registry.

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recommendations! Published in 2022 at "JAMA dermatology"

DOI: 10.1001/jamadermatol.2022.4639

Abstract: Importance The registered dose of dupilumab for adult patients with atopic dermatitis (AD) is 300 mg every other week. At present, it is unknown whether serum dupilumab levels are associated with treatment response or adverse… read more here.

Keywords: adverse effects; serum dupilumab; treatment response; dupilumab levels ... See more keywords
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An Overview of Cancer Drugs Approved by the US Food and Drug Administration Based on the Surrogate End Point of Response Rate.

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recommendations! Published in 2019 at "JAMA internal medicine"

DOI: 10.1001/jamainternmed.2019.0583

Abstract: Importance Approximately one-third of cancer drugs are approved based on response rate (RR)-the percentage of patients whose tumors shrink beyond an arbitrary threshold-typically assessed in a single-arm study. Objective To characterize RR end points used… read more here.

Keywords: cancer drugs; response; drug; rate ... See more keywords
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A US National Study of the Association Between Income and Ambulance Response Time in Cardiac Arrest

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recommendations! Published in 2018 at "JAMA Network Open"

DOI: 10.1001/jamanetworkopen.2018.5202

Abstract: Key Points Question Are ambulance 9-1-1 times longer in high-income compared with low-income areas, and how do response times compare with national benchmarks across income quartiles? Findings In this US national, cross-sectional study of 63 600… read more here.

Keywords: response; study; cardiac arrest; ambulance ... See more keywords
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Evaluation of Programmed Death Ligand 1 (PD-L1) Gene Amplification and Response to Nivolumab Monotherapy in Non-small Cell Lung Cancer.

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recommendations! Published in 2020 at "JAMA network open"

DOI: 10.1001/jamanetworkopen.2020.11818

Abstract: Importance Robust predictors for response to anti-programmed death 1 and its ligand (PD-1/PD-L1) immunotherapy in non-small cell lung cancer (NSCLC) are not fully characterized. Objective To evaluate whether PD-L1 (CD274) copy number gains (CNGs), comprising… read more here.

Keywords: nivolumab monotherapy; response; response nivolumab; programmed death ... See more keywords
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Chicago's Stay-at-Home Mandate-The Need to Improve on Domestic Violence Prevention and Response.

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recommendations! Published in 2021 at "JAMA network open"

DOI: 10.1001/jamanetworkopen.2021.22327

Abstract: The novel coronavirus, SARS-CoV-2, has led to profound changes in the human condition, including how we socially and physically relate following stay-at-home (SH) mandates. For some individuals, SH mandates were a refreshing break from business… read more here.

Keywords: violence; response; mandate; stay home ... See more keywords
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Response-Adapted Treatment Following Radiotherapy in Patients With Resectable Locally Advanced Hypopharyngeal Carcinoma

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recommendations! Published in 2022 at "JAMA Network Open"

DOI: 10.1001/jamanetworkopen.2022.0165

Abstract: Key Points Question Is a response-adapted strategy based on early tumor response to radiotherapy associated with improved survival with a functional larynx in patients with resectable locally advanced hypopharyngeal carcinoma? Findings In this cohort study… read more here.

Keywords: locally advanced; radiotherapy; response adapted; patients resectable ... See more keywords