Item Response Analyses of the Children's Depression Rating Scale-Revised Using Data from Clinical Studies.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of child and adolescent psychopharmacology"
DOI: 10.1089/cap.2021.0141
Abstract: Objective: We aimed to identify which of the 17 items comprising the Children's Depression Rating Scale-Revised (CDRS-R) can sensitively capture changes in depression severity. Methods: We used data from four studies involving two antidepressants. For… read more here.
Keywords: depression; group; response analyses; cdrs ... See more keywords
Population pharmacokinetic (PK) and exposure-response analyses from the pivotal ALTA-1L study: Model-based analyses supporting the brigatinib dose in patients with anaplastic lymphoma kinase (ALK)–positive non–small cell lung cancer (NSCLC).
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2020.38.15_suppl.e21725
Abstract: e21725Background: Brigatinib is a next-generation ALK tyrosine kinase inhibitor (TKI) with differential activity by dose (90 mg vs 180 mg [with a 7-day lead-in at 90 mg] qd) in the phase 2 post-cri... read more here.
Keywords: exposure response; alk; response analyses; kinase ... See more keywords