Evidence of an interaction between FXR1 and GSK3β polymorphisms on levels of Negative Symptoms of Schizophrenia and their response to antipsychotics
Sign Up to like & getrecommendations! Published in 2021 at "European Psychiatry"
DOI: 10.1192/j.eurpsy.2021.26
Abstract: Abstract Background Genome-Wide Association Studies (GWASs) have identified several genes associated with Schizophrenia (SCZ) and exponentially increased knowledge on the genetic basis of the disease. In addition, products of GWAS genes interact with neuronal factors… read more here.
Keywords: fxr1 gsk3; response antipsychotics; fxr1; interaction ... See more keywords
Blood Gene Expression Profile Predicts Response to Antipsychotics
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Molecular Neuroscience"
DOI: 10.3389/fnmol.2018.00073
Abstract: Antipsychotic drugs are one of the largest types of prescribed drugs and have large inter-individual differences in efficacy, but there is no methodology to predict their clinical effect. Here we show a four-gene blood expression… read more here.
Keywords: response; expression profile; treatment; response antipsychotics ... See more keywords